July 28, 2024
Jonathan David, Aviva Berkovich-Ohana, Yair Dor-Ziderman
2 citations
preprint
Background: How the human psyche interacts with the theme of death is fundamental to individual and societal life, profoundly influencing cognition, affect, and behavior. Death-related psychological phenomena, such as death anxiety and acceptance, have been shown in clinical studies to be influenced by psychedelic (LSD and psilocybin) interventions. However, the literature lacks a comprehensive...
JMIR Formative Research
July 25, 2024
Ioannis Iliakis, Maria Anagnostouli, George P Chrousos
1 citation
Multiple sclerosis (MS) is a chronic inflammatory disease affecting the central nervous system, often leading to poor sleep quality and diminished quality of life (QoL) for affected patients. Sleep disturbances in MS do not always correlate linearly with other symptoms such as anxiety, depression, fatigue, or pain. Various approaches, including stress reduction techniques such as...
Journal of Advances in Medicine and Medical Research
July 24, 2024
Ibrahim Lanre Folorunsho, Nkechinyere Mary Harry, Chukwubueze Obiajunwa et al.
Post-Traumatic Stress Disorder (PTSD) is a debilitating mental health condition that can occur after experiencing or witnessing a traumatic event. The impact of PTSD extends beyond the individual, affecting families, communities, and society as a whole. This study aims to investigate the potential of psilocybin as a treatment for PTSD. Psilocybin, after being metabolized to psilocin, binds to...
Frontiers in Psychiatry
July 16, 2024
André Do, Vanessa Michaud, Jean-François Stephan et al.
3 citations
Psilocybin has reemerged as a promising treatment for difficult-to-treat depression (DTD). Although there is limited evidence regarding interactions between psilocybin and other psychotropic drugs, clinical trials require that patients discontinue their antidepressants before study entry to isolate the benefits of psilocybin and to minimize the risk of adverse events. We present the first case...
Journal of Anesthesia and Translational Medicine
July 11, 2024
Kenji Hashimoto, Mingming Zhao, Tingting Zhu et al.
32 citations
Ketamine, a dissociative anesthetic, is widely utilized in both human and veterinary anesthesia. Its (S)-enantiomer, esketamine, is similarly employed for anesthesia and analgesia. The anesthetic effects of both ketamine and esketamine arise from their antagonism of the N-methyl-D-aspartate receptor (NMDAR). In field of psychiatry, the rapid-acting antidepressant properties of ketamine for...
International Journal of Environmental Research and Public Health
July 7, 2024
Beverley Martin, Blake Peck, Daniel Terry
5 citations
Contemplative pedagogy, specifically yoga, introduced into the higher education curriculum has the potential to develop and entrain intellectual, emotional, and social development in relation to mental health among university students studying for medical and nursing degrees. The objective of the study is to determine the extent of the current literature on the prevalence of yoga as a...
Scientific Reports
July 1, 2024
Jonathan N. Davies, Anna Faschinger, Julieta Galante et al.
45 citations
Meditation, yoga, guided imagery, and progressive relaxation are promoted as complementary approaches for health and wellbeing in the United States, but their uptake by different sociodemographic groups is unclear. This study assessed the prevalence and 20 year trends in the use of these practices in US adults between 2002-2022. We examined practice use and associations with sociodemographic...
Neuropharmacology
July 1, 2024
Kevin T Krupp, Jazmine D W Yaeger, Leighton J Ledesma et al.
11 citations
Psychedelic compounds have potentially rapid, long-lasting anxiolytic, antidepressive and anti-inflammatory effects. We investigated whether the psychedelic compound (R)-2,5-dimethoxy-4-iodoamphetamine [(R)-DOI], a selective 5-HT2A receptor partial agonist, decreases stress-related behavior in male mice exposed to repeated social aggression. Additionally, we explored the likelihood that these...
Journal of pharmacy & bioallied sciences
July 1, 2024
Jayalakshmi Lakshmanan, Bhuvaneswari Gopalakrishnan, Shankar Shanmugam Rajendran
1 citation
The global demographic shift toward an older population is witnessing an increase in age-related psychological disorders and chronic illnesses, particularly among those residing in old age homes. Mind-body interventions (MBIs) have shown promise in enhancing mental and physical health without the adverse effects associated with pharmaceuticals. This quasi-experimental study involved 42 elderly...
Psychopharmacology
July 1, 2024
Dilan Gokalp, Gunes Unal
Ketamine produces dissociative, psychomimetic, anxiolytic, antidepressant, and anesthetic effects in a dose dependent manner. It has a complex mechanism of action that involve alterations in other glutamate receptors. The metabotropic glutamate receptor 5 (mGluR5) has been investigated in relation to the psychotic and anesthetic properties of ketamine, while its role in mediating the...