Acta Neuropsychiatrica
September 3, 2025
Filipe Reis Teodoro Andrade, Tobias Buchborn, Gabriel Thalheimer et al.
3 citations
Abstract Background: Major depressive disorder (MDD) is a significant public health concern, and current treatments often have limitations in effectiveness and adherence. Psilocybin, a psychedelic compound found in certain mushrooms, is being explored as a potential treatment for depression. It primarily acts through the serotonin 5-HT2A receptor but interacts with 5-HT1A and 5-HT2C receptors....
Mindfulness
September 1, 2025
Lorena Desdentado, Marta Miragall, Ausiàs Cebolla et al.
Abstract Objectives This study aimed to (1) investigate the feasibility of three online-delivered mindfulness practices that emphasize different types of attentional focus: visceral body scan (VBS), somatosensory body scan (SBS), and external (non-body) meditation (ECM), and (2) gain insight into the potential effects of these interventions on interoceptive and other psychological outcomes....
Human Psychopharmacology: Clinical and Experimental
September 1, 2025
Renée Martin-Willett, Carillon J. Skrzynski, Angela D Bryan et al.
This study examined the effects of tetrahydrocannabinol (THC) and cannabidiol (CBD) on negative mood and drinking behaviors, and whether those effects were moderated by levels of perceived discrimination among participants who identify with a racial, ethnic, gender, or sexual identity that is underrepresented in research. Participants were either not using cannabis, using cannabis with THC, or...
Frontiers in Nutrition
August 21, 2025
Jakub Słupski, Agnieszka Mechlińska, Adam Włodarczyk et al.
1 citation
Mood disorders, including major depressive disorder (MDD) and bipolar disorder (BP), significantly impact global health, with MDD affecting over 300 million people and BP affecting approximately 2% of the world's population. Ketamine, originally an anesthetic, has emerged as a promising treatment for patients with treatment-resistant depression (TRD), due to its unique pharmacological...
Healthcare
August 14, 2025
Fei-Wen Lin, Ya-Hui Yang, Jiun-Yi Wang
Background: Anxiety and stress are common mental health issues that affect both psychological and physiological well-being as well as quality of life. The Tibetan Singing Bowl, which combines sound and vibration, is often used in meditation and relaxation and may offer therapeutic benefits. However, current research findings are scattered and lack systematic integration and quantitative...
Medical Sciences
August 13, 2025
Adam Siebieszuk, Adam Filip Płoński, Marcin Baranowski
2 citations
Modern society faces a growing prevalence of mental disorders, with stress emerging as a critical factor affecting mental well-being. In recent years, breathwork has gained public and scientific recognition as a promising approach for enhancing psychological health. Despite the rapid growth in research, the field remains fragmented due to the diversity of breathing techniques. Moreover, recent...
American Psychologist
August 7, 2025
J. David Creswell, Simon B. Goldberg
14 citations
Smartphone-based meditation training has jumped onto the world stage, shifting how millions of people learn and practice meditation. This review examines the rapid proliferation of meditation apps and synthesizes current scientific findings on their usage patterns, efficacy, mechanisms of action, and safety. Though research lags well behind public adoption, recent randomized controlled trials...
Frontiers in Psychiatry
August 6, 2025
Grace Blest‐hopley, Giuseppe Pasculli, Simon Ruffell et al.
3 citations
Introduction Psilocybin, a serotonergic psychedelic, has shown therapeutic potential in treating mental health disorders by, amongst the many effects, promoting neuroplasticity and reorganising functional connectivity across cortical and subcortical networks involved in emotion and cognition. Veterans with traumatic brain injuries (TBI) often experience chronic neurological and psychological...
Frontiers in Psychiatry
August 4, 2025
Wierzbicka Małgorzata, Renata Kopczyk, Alexander L. Gerlach et al.
1 citation
Depression prevalence is markedly elevated in oncological patients, particularly among head and neck cancer (HNC) cohorts, who face twice the prevalence of major depressive disorder (MDD) compared to other cancer populations. MDD in this context independently predicts poorer clinical outcomes and increased morbidity. HNC management often involves acute surgical interventions with disfiguring...
EClinicalMedicine
August 1, 2025
Patricia M Livingston, Natalie Winter, Lahiru Russell et al.
Fear of cancer recurrence (FCR) is a prevalent and debilitating condition that effects around 60% of people living with cancer. It is severe, persistent, and imposes a significant financial burden on the healthcare system. Given FCR's profound impact on mental health and quality of life, adopting targeted interventions to mitigate its effects is essential. This study reports on the efficacy of...