Based on animal data, NMDA receptor hypofunction has been suggested as a model for positive symptoms in schizophrenia. NMDA receptor hypofunction affects several corticolimbic brain regions, of which the posterior cingulate seems to be the most sensitive. However, empirical support for a crucial role of posterior cingulate NMDA hypofunction in the pathophysiology of positive symptoms is still...
The fundamental revelations to the founders of the three monotheistic religions, among many other revelation experiences, had occurred on a mountain. These three revelation experiences share many phenomenological components like feeling and hearing a presence, seeing a figure, seeing lights, and feeling of fear. In addition, similar experiences have been reported by non-mystic contemporary...
Reviewed by: In the Houses of the Holy: Led Zeppelin and the Power of Rock Music John V. Walker (bio) Susan Fast. In the Houses of the Holy: Led Zeppelin and the Power of Rock Music Oxford University Press 2001. vii, 248. $22.00 The prologue of Marcus Boon's The Road of Excess: A History of Writers on Drugs, aside from violating the unwritten law that the PhD candidate's tortuous attempt to...
Many tryptamine derivatives are known to induce altered states of consciousness and are increasingly of interest in forensic and neurobiological studies. The analytical chemistry of certain synthetic routes to the tryptamines is discussed and likely side products and impurities identified, where literature reports are available. Recent examples from the authors' laboratory are presented to...
“While the neurophysiological and neurochemical bases of dreams will ultimately be uncovered, a full understanding requires an explanation of dream content that makes sense in both psychological and neurobiological terms.” Payne and Nadel 2004 First, Ken Paller (Paller and Voss 2004) is to be congratulated for bringing together a prime and comprehensive group of researchers for this special...
kappa-opioid receptors (KORs) represent the principal site of action of dynorphin and related neuropeptides. Recently, Salvinorin A--a naturally occurring neoclerodane diterpene hallucinogen was identified to be a highly selective KOR agonist. In this brief review we summarize the known chemistry, pharmacology and biology of salvinorin A. Because salvinorin A profoundly alters human...
August 30, 2004R. Stein, Philip L. Stein, Benjamin R. Kracht et al.
1 The Anthropological Study of Religion 1 The Anthropological Perspective 1 The Holistic Approach The Study of Human Societies The Fore of New Guinea: An Ethnographic Example Two Ways of Viewing Culture Cultural Relativism BOX 1.1 * Karen McCarthy Brown and Vodou The Concept of Culture The Study of Religion Attempts at Defining Religion The Domain of Religion Theoretical Approaches to the Study...
Because psychoactive plants exert profound effects on human perception, emotion, and cognition, discovering the molecular mechanisms responsible for psychoactive plant actions will likely yield insights into the molecular underpinnings of human consciousness. Additionally, it is likely that elucidation of the molecular targets responsible for psychoactive drug actions will yield validated...
RationaleDuring binocular rivalry, two incompatible images are presented to each eye and these monocular stimuli compete for perceptual dominance, with one pattern temporarily suppressed from awareness. One variant of stimulus presentation in binocular rivalry experiments is dichoptic stimulus alternation (DSA), when stimuli are applied to the eyes in rapid reversals. There is preliminary...