PsychopharmacologyApril 2014Reagan R Wetherill, Anna Rose Childress, Kanchana Jagannathan et al.
Addiction theories posit that drug-related cues maintain and contribute to drug use and relapse. Indeed, our recent study in cocaine-dependent patients demonstrated that subliminally presented cocaine-related stimuli activate reward neurocircuitry without being consciously perceived. Activation of reward neurocircuitry may provoke craving and perhaps prime an individual for subsequent...
Epidemiological findings suggest that, relative to adults, adolescents are more vulnerable to the adverse persistent effects of cannabis on working memory. However, the potential confounds inherent in human studies preclude direct determination of a cause-and-effect relationship between adolescent cannabis use and heightened susceptibility to persistent working memory impairments. Consequently,...
BACKGROUND: The aim of this study was to investigate whether the perception of experimental pain was different during a mindfulness manipulation than during a distraction manipulation. Furthermore, it was examined if effects were moderated by dispositional pain catastrophizing. METHODS: Undergraduate students (n = 51) completed self-report measures of pain catastrophizing and mindfulness....
Theoretical models have suggested an association between the ongoing experience of the world from the perspective of one's own body and hippocampus-based episodic memory. This link has been supported by clinical reports of long-term episodic memory impairments in psychiatric conditions with dissociative symptoms, in which individuals feel detached from themselves as if having an out-of-body...
This article proposes a new model to interpret seemingly conflicting evidence concerning the correlation of consciousness and neural processes. Based on an analysis of research of blindsight and subliminal perception, the reorganization of elementary functions and consciousness framework suggests that mental representations consist of functions at several different levels of analysis, including...
Central nervous system (CNS) damage associated with psychostimulant dependence may be an ongoing, degenerative process with adverse effects on neuropsychiatric function. However, the molecular mechanisms regarding how altered energy regulation affects immune response in the context of substance use disorders are not fully understood. This review summarizes the current evidence regarding the...
Abstract The Stoic three-fold classification of dreams provided Philo with a structure upon which he built his treatise on Dreams. This treatise was meant to comment on the dreams appearing in the book of Genesis, in the strict order of their appearance in the Scripture. The classification as presented by him added a gradation which classifies dreams by their phenomenology and the clarity of...
Cannabinoid exposure during adolescence has adverse effects on neuroplasticity, emotional behavior, cognition, and reward sensitivity in adult rats. We investigated whether escalating doses of the cannabinoid receptor 1 (CB1 R) agonist, HU-210, in adolescence would affect adult hippocampal neurogenesis and behavioral processes putatively modulated by hippocampal neurogenesis, in adult male and...
The Colorful Depictions of God in Mystical Consciousness1 Paul C. Martin (bio) Introduction In 1960 Walter T. Stace suggestively wrote that “[t]here are underground connections between the mystical and the aesthetic (whether in poetry or in other forms of art) which are at present obscure and unexplained.”2 Since that statement there has been tremendous work done by commentators and scholars on...
We are grateful to Orme-Johnson and Dillbeck (2014) for raising several potential methodological concerns they have with our meta-analysis of the psychological effects of meditation and for thereby providing us with the opportunity to clarify these points. Orme-Johnson and Dillbeck raised 4 points that they believed might have led to unfair treatment of studies that reported the effects of...