In this review, studies focusing on the therapeutic use of psychedelics for treating mental health disorders published since 2010 have been examined. A systematic literature search was conducted using Medline and EBSCO. After extracting data from 19 papers, an analysis was performed. Critical evidence highlighting the effectiveness of psychedelic drugs in treating depression, anxiety,...
Abstract Psilocybin is a psychedelic tryptamine that has emerged as a potential candidate for the treatment of a variety of conditions, including treatment resistant depression and post-traumatic stress disorder. Clinical trials which have assessed the efficacy of psilocybin for these conditions report a rapid and sustained improvement in patient- and clinician-rated depression scores. The...
Drug-related dreams are defined as dreams experienced by individuals with a substance use disorder during the withdrawal or recovery process. Studies indicate that authors interpret all drug-related dreams as reflections of the attempts by individuals with addiction to fulfill their drug use desires at varying levels of satisfaction. The absence of an explanation in the literature regarding the...
Recent studies indicate that nitrous oxide (N2O), a gaseous anesthetic and an NMDA (N-methyl-D-aspartate) receptor antagonist, produces rapid antidepressant effect in patients suffering from treatment-resistant depression. Our recent work implies that hypothermia and reduced energy expenditure are connected with antidepressant-induced activation of TrkB neurotrophin receptors - a key regulator...
Abstract: This article aims to present "iboga," also known as "sacred wood," as an endogenous knowledge used traditionally in the spiritual and medicinal rituals of the people of Gabon during initiation ceremonies such as bwiti, mumbwiri, and many other rites. This plant, considered a natural, cultural, and national heritage, allows for transcendence between physical and invisible worlds...
Chronic restrain stress (CRS) induces depression-like behaviors and demyelination in the brain; however, the relationship between these depression-like behaviors and demyelination remains unclear. Arketamine, the (R)-enantiomer of ketamine, has shown rapid antidepressant-like effects in CRS-exposed mice. We examined whether arketamine can improve both depression-like behaviors and demyelination...
The novel antidepressant arketamine, the (R)-enantiomer of ketamine, has been shown to ameliorate demyelination and facilitate remyelination in the brains of cuprizone (CPZ)-treated mice. However, the mechanisms behind its effects remain unclear. Given the role of transforming growth factor β1 (TGF-β1) in arketamine's antidepressant-like effects, we examined whether TGF-β1 also plays a role in...
Research has demonstrated that meditation boosts people’s mental and physical wellness. Response to meditation is a subjective phenomenon. The EEG signal offers profound insight into the underlying alterations in brain activity in response to various meditative forms. This study aims to find out the effect of mediation on relaxation and the longevity of relaxation caused by meditation based on...
Conscious (subjective) experience permeates our daily lives, yet general consensus on a theory of consciousness remains elusive. Integrated Information Theory (IIT) is a prominent approach that asserts the existence of subjective experience (0th axiom), from an intrinsic system of causally related units, and five essential properties (axioms 1-5): intrinsicality, information, integration,...
Pustaka KesehatanDecember 12, 2024Inke - Kusumastuti, I Wayan Westa, I Made Wedastra
Working as an addiction counselor involves specific challenges that might increase one's predisposition to suffering from psychopathology. Therefore, it is paramount for counselors to maintain holistic self-care and self-improvement. The mindfulness approach has good efficacy for improving the wellness of the clinical population, but data regarding its use for health workers, including...