Cureus
October 1, 2024
Priyadarsini Samanta, Ipsa Mohapatra, Rituparna Mitra et al.
6 citations
In recent years, Internet Addiction Disorder (IAD) has become a major mental health concern among adolescents, with detrimental effects on social relationships, academic performance, and emotional well-being. The focus of mindfulness-based interventions (MBIs) on improving self-awareness, emotional regulation, and cognitive flexibility has drawn interest in MBIs as possible therapeutic...
Australian & New Zealand Journal of Psychiatry
October 1, 2024
Alistair Carroll, Adam Bayes, Mark Montebello et al.
10 citations
Ketamine is a restricted and regulated medication in Australia and New Zealand, which has implications when considering treatment for patients with treatment-resistant depression and a history of illicit drug use, abuse or dependence. Regulations governing prescription of ketamine for treatment-resistant depression vary between jurisdictions in Australia and New Zealand, though most restrict...
Contemporary Clinical Trials Communications
October 1, 2024
Erica Eaton, Christy Capone, Brian J Gully et al.
2 citations
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) commonly co-occur and are associated with more severe symptomatology than either disorder alone, increased risk of suicide, and poorer response to existing treatments. A promising therapeutic intervention is the integration of 3,4-methylenedioxymethamphetamine (MDMA) and psychotherapy. The Food and Drug Administration (FDA)...
CNS Drugs
October 1, 2024
Anton Gomez-Escolar, Daniel Folch-Sanchez, Joanna Stefaniuk et al.
16 citations
Mental health disorders and substance use disorders (SUDs) in particular, contribute greatly to the global burden of disease. Psychedelics, including entactogens and dissociative substances, are currently being explored for the treatment of SUDs, yet with less empirical clinical evidence than for other mental health disorders, such as depression or post-traumatic stress disorder (PTSD). In this...
European Addiction Research
September 25, 2024
Ioanna A. Vamvakopoulou, David Nutt
13 citations
Background: Psychedelic substance use in ritualistic and ceremonial settings dates back as early as 8,500 BCE. Only in recent years, from the mid-20th century, we have seen the re-emergence of psychedelics in a therapeutic setting and more specifically for the treatment of addiction. This article aims to review research over the past 40 years using classic (psilocybin, lysergic acid...
European journal of organic chemistry
September 23, 2024
Alexander J Hughes, Charles R Hamelink, Steven D Townsend
5 citations
The iboga alkaloids are a family of monoterpene indole alkaloids first discovered from the root of Tabernanthe iboga. The major alkaloid constituent in the root, ibogaine, has garnered interest for its anti-addictive properties. Ibogaine has been shown to reduce opiate, amphetamine, alcohol, and nicotine self-administration in rodents. However, ibogaine itself is less than optimal as a...
Annals of Indian Psychiatry
September 3, 2024
Nidhi Purushottum Marvania, Anto Leroy Rayan, Dhruti Vijaykumar Merchant et al.
3 citations
Background: Alcohol use disorders (AUDs) are emerging as a substance use disorder having various psychological and physical ill effects leading to hampering of individual’s productivity and functioning. Aims: The aim of this study was to evaluate the efficacy of ketamine in enhancing confidence levels to abstain from alcohol. Methods: Eighteen patients were administered ketamine intravenously...
Current Psychology
September 1, 2024
Paul Barrows, William van Gordon, Miles Richardson
AbstractSelf-transcendence and the associated decrease in ego-centeredness are understood to foster altruistic and positive behaviors that promote prosociality and pro-environmental actions. However, the lack of an agreed valid and reliable measure of self-transcendence has posed difficulties in examining this subject. The main aim of this study was to use the recently developed Ontological...
Journal of Psychiatric Research
September 1, 2024
Noah R Wolkowicz, Mehmet Sofuoglu, Brian Pittman et al.
Attentional bias (AB) is believed to be an important factor in the development and maintenance of both opioid use disorder (OUD) and chronic pain. Cannabis and its main psychoactive constituent, delta-9-tetrahydrocannabinol (THC), produce analgesic effects via processes that are potentially relevant to AB and is commonly used by persons with OUD. This exploratory study investigated if THC...
Journal of Studies on Alcohol and Drugs
September 1, 2024
Sisi Li, Taylor Kurtzweil, Shahin Shams et al.
3 citations
Recent research has shown potential for psychedelic therapeutics as addiction treatments; however, some academic institutions, commercial entities, and individuals are attempting to monopolize psychedelic compounds through exploiting the patent process. This Perspective article describes efforts that have been devised to mitigate exclusionary patent practices pertinent to psychedelic...