Bangladesh Journal of Psychiatry
October 5, 2026
Mohammad Shamsul Ahsan, Leuza Mubassara, Ananya Kar et al.
Depressive episodes are common but has great impact either in unipolar or bipolar mood disorder. Medical management of severe depression with suicidal attempts are challenging. The rate of Major Depressive Disorder (MDD) who are non-responders are about 30% of those receiving treatment in research settings. Over the past 15 years, ketamine infusions have demonstrated rapid antidepressant and...
Journal of Addiction Medicine
October 5, 2026
Samuel Sukmin Yang, Rachel Goud, Jeremy Weleff
Ketamine has gained increasing attention for its therapeutic potential, yet concerns remain regarding its misuse and the associated complications of its use. Ketamine use and ketamine use disorder can induce psychotic symptoms, but the persistence of such symptoms with chronic use and effective treatment of these symptoms is poorly characterized. Although case reports of ketamine use and...
Issues in Mental Health Nursing
October 5, 2026
JoEllen Schimmels, Madison Nobbs
As interest in psychedelic-assisted therapies grows ahead of regulatory standardization, mental health nursing stands at a critical clinical and professional inflection point. This state-of-the-science review examines psychedelic-assisted therapies through a mental health nursing lens and advocates for the formal recognition of psychedelic nursing as a specialty with defined competencies,...
Frontiers in Psychiatry
October 5, 2026
Andreas Paris, Foteini Thoma, Aikaterini Velentza et al.
Recent advances in psychedelic research have renewed interest in the potential therapeutic role of psychedelic-assisted interventions in psychiatry. Early clinical trials suggest that compounds such as psilocybin and MDMA, administered within structured therapeutic frameworks, may produce rapid symptom improvements for conditions including depression, post-traumatic stress disorder, and...
Basic & Clinical Cancer Research
October 4, 2026
Arman Ryahin, Kaveh Ebadi, Farhad Azadmehr
Background: Breast cancer is the most common invasive cancer among women world- wide. While advancements in early diagnosis and treatment have improved survival rates, many breast cancer patients experience persistent sleep disturbances, anxiety, and stress, which negatively impact their quality of life. Pharmacological treatments for sleep disor- ders pose risks such as dependency and side...
Zenodo (CERN European Organization for Nuclear Research)
October 4, 2026
Piotr Świder
preprint
This paper examines whether advanced large language models operating under enhanced deliberative regimes, here termed Reasoning Language Models (RLMs), possess minds under an explicitly defined functional account. We develop an operational definition informed by Newell’s account of cognitive organization and Gärdenfors’s theory of conceptual spaces, together with research on mental models,...
PsyArXiv
October 3, 2026
Rebekah Senānāyaka
preprint
Ninety percent of human societies practise institutionalised alterations of consciousness. Across independent traditions, communities that develop governed protocols for sustained engagement with non-human organisms produce practitioners whose hybrid consciousness becomes the basis of social authority. Drawing on 27 months of apprenticeship-based fieldwork in the Peruvian and Colombian Amazon...
Zenodo (CERN European Organization for Nuclear Research)
October 3, 2026
Roberto García Sánchez
preprint
Consciousness is increasingly linked to large-scale neural dynamics characterized by integration, differentiation, recurrence and criticality. However, the cellular bioenergetic mechanisms that constrain these dynamics remain underexplored. In this review, we propose a neurometabolic criticality framework in which mitochondrial function acts as a regulatory interface between cellular metabolism...
Journal of Substance Use
October 3, 2026
Philip George Harris
Background Ketamine use has increased in recent years, with growing recognition of associated physical, psychological, and cognitive harms. Existing assessment approaches, largely derived from dependence-based models, may be insufficiently sensitive to the multi-domain and progressive nature of ketamine-related harm, particularly in its earlier stages.Methods A vignette-based inter-rater...
October 2, 2026
Barry Tse
preprint
Introduction: Mindfulness-based programs (MBPs) are commonly organized around eight weeks, yet direct experimental evidence on the consequences of varying this architecture is sparse. In a contextual inventory of 39 established programs, 11 of the 15 with an unqualified fixed-week structure used eight weeks.Methods: This rapid review examined direct evidence on assigned program length, session...