BMC Medical Ethics
October 18, 2026
Adrian Kind, Josephine Görke, Hannah Smirr et al.
Abstract Background Treatments with acute consciousness-altering effects, such as (es)ketamine, place patients in a state of heightened vulnerability with reduced capacity for self-advocacy and self-regulation. Since feeling safe is a precondition for consenting to begin, and remaining in, treatment, this raises distinct ethical demands on care. Which features of the setting enable patients to...
World Journal of Pharmaceutical Research
October 16, 2026
2Dr. Suman Sarkar *1Dr. Mukesh Kumar
preprint
Background: The clinical apparatus of Ayurveda is commonly understood through the lens of Laukiki Cikitsa (worldly therapeutics), which works primarily to restore bio-humoral equilibrium using pharmacological substances (Yuktipavyapasraya), spiritual rituals (Daivavyapasraya), and disciplined mental restraint (Sattvavajaya). Nevertheless, the foundational tantrakaras recognized that therapeutic...
Medicine, Health Care, and Philosophy
October 16, 2026
Drew Leder, Kevin Aho
Illness is often understood as a disruption of ordinary temporality, fracturing narrative continuity, constricting horizons of possibility, and immersing sufferers in the slow, uncertain rhythms of waiting. Drawing on phenomenology, existential philosophy, pathography, and East Asian wisdom traditions, this article examines the relationship between growing ill and growing still, being a patient...
bioRxiv (Cold Spring Harbor Laboratory)
October 16, 2026
Janis Karan Hesse, Frank F Lanfranchi, Conor McGrory et al.
preprint
Summary The neural correlates of consciousness remain elusive 1 . Previous studies found that high-level visual cortex is weakly modulated by conscious perception 2,3 , yet a pure signal of conscious perception has not been found anywhere in the brain. Here, we employed Neuropixels recordings across multiple face patches in inferotemporal and prefrontal cortex during a binocular flash...
Humanities and Social Sciences Communications
October 16, 2026
Qingchen Guo
The rapid integration of Large Language Models has triggered a global policy dilemma regarding anthropomorphism and user dependency. Because this regulatory challenge is closely tied to an unresolved conceptual ambiguity concerning the nature of AI, this article introduces a phenomenological framework to delineate the essential character of synthetic cognition. To this end, we demonstrate a...
Zenodo (CERN European Organization for Nuclear Research)
October 16, 2026
Jeremy Rodgers
preprint
When a person compares two apparent sizes, what warrants saying that their relation actually appears, and that the organised physical comparison itself bears that appearance? This two-document research contribution develops a positive, explicitly scoped answer. It distinguishes producing a correct comparison, experiencing a relation, and identifying the physical activity that bears the...
Zenodo (CERN European Organization for Nuclear Research)
October 16, 2026
Anna Fernando
preprint
BACKGROUND AND AIMS:Contemporary addiction models typically treat craving as a persistent vulnerability requiring ongoing management. This N-of-1 case study examines whether intensive Satipaṭṭhāna (mindfulness) practice can alter the experiential structure of craving itself, rather than merely helping a person tolerate or redirect it. METHODS:Longitudinal self-observation by a physician with...
Alcoholism & Drug Abuse Weekly
October 16, 2026
Alison Knopf
A nationally representative cross‐sectional survey of U.S. adults found the among all psychedelics, ibogaine and 5‐MeO‐DMT (5‐methoxy‐N,N‐ dimethyltryptamine) resulted in the most frequent self‐reported adverse outcomes, according to a recent study. The study, “Adverse Health Outcomes of Psilocybin, LSD, MDMA, Ibogaine, and 5‐MeO‐DMT,” by Otto Simonsson, Ph.D., and colleagues, was published...
CIENCIAMATRIA
October 15, 2026
Tammy Isabel Fiallos-Ramírez, Luis Leandro Campaña-Poveda, Walter Alberto Vayas-Valdivieso
Chronic stress induces epigenetic changes that favour inflammation and disease risk, while mindfulness has become established as a stress-reduction strategy. The study therefore aimed to analyse the relationship between mindfulness practice and the epigenetic processes linked to stress, inflammation and cellular ageing within public health. A systematised literature review of clinical trials,...
Zenodo (CERN European Organization for Nuclear Research)
October 15, 2026
Vladimir Yakunin
preprint
This document describes agents, and consciousness-like organization as a further special case,through their latent spaces. A system has a latent space Z: a compressed description of the stateof the world, of its carrier, and of its own computation. A latent is always a description of somesubsystem of an underlying substrate at some scale. It is not a primitive object and it is not assumedto be...