Zenodo (CERN European Organization for Nuclear Research)
May 29, 2026
Andrew Stewart Caldin
E8 ANALYSIS PIPELINE — derived from: PRESSMAN Breaking Source URL: https://www.theguardian.com/science/2026/may/18/magic-mushrooms-treatment-cocaine-addiction-study The E8 geometry framework supplies a high‑dimensional root‑vector algorithm that can encode the coupled dynamics of serotonin‑2A receptor activation and dopamine pathways implicated in cocaine addiction. By embedding the...
Translational Psychiatry
May 26, 2026
Marvin M. Urban, Lea Zillich, Nathalie M. Rieser et al.
1 citation
The serotonergic hallucinogen psilocybin has shown potential as a treatment for psychiatric conditions like alcohol use disorder (AUD) and depression in clinical studies. Epigenetic mechanisms, including DNA methylation, are hypothesized to contribute to its lasting therapeutic benefits. In this exploratory study, we present the first methylome-wide analysis of psilocybin-induced changes in a...
Journal of Psychoactive Drugs
May 22, 2026
Jamie Walker, Daryle Deering, Bruno Hamish Unger
Opioid dependence is a public health concern in New Zealand, with limited treatment options beyond opioid substitution therapy (OST). Ibogaine, a psychoactive alkaloid with reported anti-withdrawal and anti-craving effects for opioid dependence, is legally available by prescription in New Zealand, offering a context for exploring user experiences. A qualitative collective case study design was...
Zenodo (CERN European Organization for Nuclear Research)
May 14, 2026
Ramin Bidari
Addiction and obsessive behaviors are commonly interpreted as disorders of the brain’s reward system. However, many dominant models in neuroscience overlook the role of the search for meaning, identity, and existential peace in intensifying these cycles. This article presents an interdisciplinary conceptual framework at the intersection of neuroscience, philosophy of consciousness, and...
Science
May 7, 2026
Rachel Nuwer
Small study that prioritized Black and low-income participants yields "remarkable" results.
Accountability in research
May 1, 2026
Katherine Cheung, Rebecca Ehrenkranz, Brian D. Earp et al.
A number of proposals across different fields have suggested incorporating "independent" actors into the research process as a way to manage potential bias. For example, in response to allegations of bias in psychedelic science, some have suggested the idea of independent auditors for adverse events, as well as the incorporation of independent researchers into the research teams of psychedelic...