Mindfulness based cognitive therapy versus treatment as usual in adults with attention deficit hyperactivity disorder (ADHD).
Lotte Janssen, Cornelis C. Kan, Pieter J Carpentier, Bram Sizoo, Sevket Hepark, Janneke Grutters, Rogier Donders, Jan K. Buitelaar, Anne E. M. Speckens
BMC Psychiatry September 15, 2015 DOI: 10.1186/s12888-015-0591-x (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial (protocol) Peer reviewed |
|---|---|
| Sample size | 120 |
| Population | Adults with ADHD |
| Interventions | Mindfulness Based Cognitive Therapy (MBCT) treatment as usual (TAU) |
| Duration | Assessments at baseline and at three, six and nine months after baseline |
| Topics | Meditation |
| Registration | NCT02463396 |
| Key findings | The protocol proposes a multi-centre randomized controlled trial to test whether adding Mindfulness Based Cognitive Therapy to treatment as usual improves clinician-rated ADHD symptom severity and secondary outcomes in 120 adults with ADHD, compared with treatment as usual alone, alongside a cost-effectiveness analysis. No outcomes are reported. |
Abstract
Adults with attention deficit hyperactivity disorder (ADHD) often present with a lifelong pattern of core symptoms that is associated with impairments of functioning in daily life. This has a substantial personal and economic impact. In clinical practice there is a high need for additional or alternative interventions for existing treatments, usually consisting of pharmacotherapy and/or psycho-education. Although previous studies show preliminary evidence for the effectiveness of mindfulness-based interventions in reducing ADHD symptoms and improving executive functioning, these studies have methodological limitations. This study will take account of these limitations and will examine the effectiveness of Mindfulness Based Cognitive Therapy (MBCT) in further detail. A multi-centre, parallel-group, randomised controlled trial will be conducted in N = 120 adults with ADHD. Patients will be randomised to MBCT in addition to treatment as usual (TAU) or TAU alone. Assessments will take place at baseline and at three, six and nine months after baseline. Primary outcome measure will be severity of ADHD symptoms rated by a blinded clinician. Secondary outcome measures will be self-reported ADHD symptoms, executive functioning, mindfulness skills, self-compassion, positive mental health and general functioning. In addition, a cost-effectiveness analysis will be conducted. This trial will offer valuable information about the clinical and cost-effectiveness of MBCT in addition to TAU compared to TAU alone in adults swith ADHD. ClinicalTrials.gov NCT02463396. Registered 8 June 2015.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cited by 11
- Mindfulness and Attention Deficit Hyperactivity Disorder The Journal of Nervous and Mental Disease July 21, 2021
- Aversive Pavlovian inhibition in adult attention-deficit/hyperactivity disorder and its restoration by mindfulness-based cognitive therapy. Frontiers in Behavioral Neuroscience 2022
- The Longitudinal Effect of Meditation on Resting-State Functional Connectivity Using Dynamic Arterial Spin Labeling: A Feasibility Study. Brain Sciences September 24, 2021
- The Feasibility, Effectiveness, and Process of Change of Mindfulness-Based Cognitive Therapy for Adults With ADHD: A Mixed-Method Pilot Study. Journal of Attention Disorders April 2020
- Mechanisms of Change in Mindfulness-Based Cognitive Therapy in Adults With ADHD Journal of Attention Disorders January 6, 2020
and 6 more in the library
Cites 9
- Using Self-Report Assessment Methods to Explore Facets of Mindfulness Assessment January 27, 2006
- Mindfulness-based cognitive therapy for depression August 21, 2006
- Neural mechanisms of attentional control in mindfulness meditation Frontiers in Neuroscience 2013
- Competence in Teaching Mindfulness-Based Courses: Concepts, Development and Assessment Mindfulness September 21, 2011
- Mindfulness-based interventions for people diagnosed with a current episode of an anxiety or depressive disorder: a meta-analysis of randomised controlled trials. PLoS One June 15, 2016
and 4 more in the library