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Cost-Utility of Attachment-Based Compassion Therapy (ABCT) and Mindfulness-Based Stress Reduction (MBSR) in the Management of Depressive, Anxious, and Adjustment Disorders in Mental Health Settings: Economic Evaluation Alongside a Randomized Controlled Trial

Francesco d’Amico, Jaime Navarrete, Jesus Montero-Marin, Eugenia Cardeñosa-Valera, Mayte Navarro‐gil, Adrián Pérez-aranda, Yolanda López-del-hoyo, Carlos Collado-Navarro, Javier García-campayo, Juan V Luciano

Mindfulness March 1, 2024 DOI: 10.1007/s12671-024-02319-4 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 90
Population Spanish patients with depressive and/or anxious disorder, or adjustment disorder with depressive and/or anxious symptomatology
Interventions Attachment-based compassion therapy (ABCT) Mindfulness-Based Stress Reduction (MBSR) treatment-as-usual (TAU)
Duration 8 weekly group sessions; 6-month follow-up
Measures EQ-5D-3L, Client Service Receipt Inventory
Topics Depression Meditation
Registration NCT03425487
Key findings Both MBSR and ABCT were more efficient than TAU alone, but the differences were not statistically significant. MBSR produced slightly higher costs (€53.69) and effects (0.004 QALYs) than ABCT, with an ICUR of €13,422.50/QALY. Both interventions significantly reduced general practice visits compared with TAU.

Abstract

Abstract Objectives The main objective of this paper was to examine the cost-utility of attachment-based compassion therapy (ABCT) compared to Mindfulness-Based Stress Reduction (MBSR) and treatment-as-usual (TAU) on patients with depressive and/or anxious disorder, or adjustment disorder with depressive and/or anxious symptomatology in terms of effects on quality-adjusted life years (QALYs) as well as healthcare costs from a public healthcare system perspective.

Method: A 6-month randomized controlled trial was conducted. Ninety Spanish patients with mental disorders (depressive, anxious, or adjustment disorders) received 8 weekly group sessions of TAU + ABCT, TAU + MBSR, or TAU alone. Data collection took place at pre- and 6-month follow-up. Cost-utility of the two treatment groups (ABCT vs MBSR vs TAU) was compared by examining treatment outcomes in terms of QALYs (obtained with the EQ-5D-3L) and healthcare costs (data about service use obtained with the Client Service Receipt Inventory).

Results: Both MBSR and ABCT were more efficient than TAU alone, although the results did not reach statistical significance. Compared to ABCT, MBSR produced an increase both in terms of costs (€53.69, 95% CI [− 571.27 to 513.14]) and effects (0.004 QALYs, 95% CI [− 0.031 to 0.049]); ICUR = €13,422.50/QALY). Both interventions significantly reduced the number of visits to general practice compared to TAU.

Conclusions: This study has contributed to the evidence base of mindfulness- and compassion-based programs and provided promising information about the cost-utility of MBSR for patients with emotional disorders. However, the small sample size and short follow-up period limit the generalizability of the findings. Preregistration Clinicaltrials.gov; NCT03425487.