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The Effects of an Online Neurofeedback‐Assisted Mindfulness‐Based Intervention (NF‐MBI) on Mental Health of Nursing Students in China: A Latent Growth Curve Modelling Analysis

Zhenwei Dai, Shu Jing, Dongxue Chen, Feifei Gao, Xue Han, Xuelin Yang, Jinglei Cheng, Tianming Chen, Zihang Feng, Zimin Han, Huan Wang, Bicheng Han, Jingjie Fan, Xiaoyou Su

International Journal of Nursing Practice November 2, 2025 DOI: 10.1111/ijn.70073 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 147
Population Chinese nursing students in Beijing, China
Intervention Mindfulness-based intervention
Duration 6-week intervention
Topics Meditation
Key findings NF-MBI reduced depression, anxiety, and fatigue and increased mindfulness in the short term; MBI increased mindfulness and reduced fatigue. Long-term, MBI showed increased depression, anxiety, and fatigue, and NF-MBI showed decreased mindfulness, compared with control.

Abstract

Background: Chinese nursing students face mental health challenges, with mindfulness-based interventions (MBI) commonly utilized to mitigate these issues. Neurofeedback-assisted MBI (NF-MBI) might be a promising alternative.

Aim: The study aims to explore the short- and long-term effectiveness of the NF-MBI and MBI in improving mental well-being among Chinese nursing students.

Methods: This three-armed randomized controlled trial included 147 nursing students in Beijing, China. MBI and NF-MBI groups completed a 6-week online MBI, with NF-MBI adding electroencephalogram-based neurofeedback. Controls received general mental education. Mental health was evaluated four times at baseline and post-intervention. Latent growth curve modeling was used to evaluate intervention effects.

Results: In the short term, the NF-MBI group exhibited decreased depression symptoms, anxiety symptoms, fatigue, and increased mindfulness. The MBI group showed increased mindfulness and decreased fatigue compared with the control group. In the long term, the MBI group showed increased depression symptoms, anxiety symptoms and fatigue. The NF-MBI group observed decreased mindfulness compared with the control group.

Conclusions: NF-MBI and MBI can effectively improve the mental health of nursing students in China, with NF-MBI performing better in certain indicators. Tailored interventions should be implemented to enhance their mental well-being.

Trial Registration: This study has been registered on the Chinese Clinical Trial Registry (ID: ChiCTR2400080314).

Comparable studies

Other randomized controlled trials on meditation, most cited first.

Study Year Design Participants
Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment 2003 Randomized controlled trial n = 41
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults 2008 Randomized controlled trial n = 139
Short-term meditation training improves attention and self-regulation Undergraduate Chinese students 2007 Randomized controlled trial n = 40
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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