Acute Leukemia With Ph1-Like Chromosome in an LSD User
JAMA September 9, 1968 DOI: 10.1001/jama.1968.03140370093024 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A user of hallucinogenic drugs who developed acute leukemia |
| Topics | LSD Mescaline |
| Keywords | Hallucinogen Leukemia Chromosome Pharmacology Molecular biology Cancer research |
| Citations | 23 |
| Key findings | A Ph1-like chromosome was found in the leukemic cells of a hallucinogenic drug user with acute leukemia. |
Abstract
Acute leukemia occurred in a user of several hallucinogenic drugs (lysergic acid diethylamide [LSD], mescaline, marihuana, and amphetamines). The leukemic leukocytes of the patient contained a Ph1-like chromosome; lymphocytes transformed with phytohemagglutinin did not show chromosome breaks. A Ph1-like chromosome has only rarely been reported in either acute leukemia or in cultured lymphocytes of individuals ingesting LSD.
Comparable studies
Other case reports and case series on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users Persons who ingested large doses of MDMA | 1991 | Case study | n = 2 |
| Further Studies in the Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Patients with mental illness | 1957 | Case series | |
| Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases People who self-administered large amounts of pure LSD powder intranasally | 1975 | Case series | n = 8 |
| Using a MDMA- and LSD-Group Therapy Model in Clinical Practice in Switzerland and Highlighting the Treatment of Trauma-Related Disorders Patients with chronic complex post-traumatic stress disorder (c-PTSD), dissociative,... | 2022 | Case series | |
| Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion | 1996 | Case series | n = 3 |
Citations in the library
Cited by 6
- LSD and Genetic Damage Science April 30, 1971
- Does LSD induce chromosomal damage and malformations? A review of the literature Teratology August 1, 1972
- Genetic toxicology of lysergic acid diethylamide (LSD-25) Mutation Research/Reviews in Genetic Toxicology 1977
- Is psychedelic use associated with cancer?: Interrogating a half-century-old claim using contemporary population-level data Journal of Psychopharmacology August 16, 2022
- Klinefelter's syndrome, LSD usage and acute lymphoblastic leukemia Clinical Genetics July 1, 1974
and 1 more in the library