Chromosomal Abnormalities in Leukocytes from LSD-25 Users
Science July 21, 1967 DOI: 10.1126/science.157.3786.313 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case-control study Peer reviewed |
|---|---|
| Sample size | 17 |
| Population | LSD-25 users and nonuser controls |
| Intervention | LSD-25 |
| Duration | 1 day to 6 months after last LSD-25 dose |
| Topics | LSD |
| Keywords | Andrology Genetics Molecular biology Physiology Toxicology Dna repair mechanisms |
| Citations | 139 |
| Key findings | LSD-25 users showed a significant increase in chromosomal abnormalities in leukocytes compared to nonuser controls. |
Abstract
A significant increase of chromosomal abnormalities was found in leukocytes from LSD-25 users (six out of eight) compared to nonuser controls (one out of nine). The two LSD-25 users showing no damage reported the lowest estimated average dose. The subjects whose cells showed damage were tested between 1 day and 6 months after their last LSD-25 dose.