Acute Leukemia With Ph1-Like Chromosome in an LSD User
JAMA September 9, 1968 DOI: 10.1001/jama.1968.03140370093024 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A user of hallucinogenic drugs who developed acute leukemia |
| Topics | LSD Mescaline |
| Keywords | Hallucinogen Leukemia Chromosome Pharmacology Molecular biology Cancer research |
| Citations | 23 |
| Key findings | A Ph1-like chromosome was found in the leukemic cells of a hallucinogenic drug user with acute leukemia. |
Abstract
Acute leukemia occurred in a user of several hallucinogenic drugs (lysergic acid diethylamide [LSD], mescaline, marihuana, and amphetamines). The leukemic leukocytes of the patient contained a Ph1-like chromosome; lymphocytes transformed with phytohemagglutinin did not show chromosome breaks. A Ph1-like chromosome has only rarely been reported in either acute leukemia or in cultured lymphocytes of individuals ingesting LSD.