Lysergic Acid Diethylamide (LSD): No Teratogenicity in Rats
Science February 16, 1968 DOI: 10.1126/science.159.3816.731 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Sample size | 89 |
| Population | Pregnant rats |
| Intervention | Lysergic acid diethylamide (LSD) |
| Dose | 1.5 to 300 micrograms |
| Topics | LSD |
| Keywords | Pregnancy Teratology Organogenesis Physiology Pharmacology Endocrinology Gestation |
| Citations | 55 |
| Key findings | LSD did not produce a greater frequency of congenital defects in rat offspring than in controls. |
Abstract
Lysergic acid diethylamide (LSD) in doses of 1.5 to 300 micrograms was given to 55 pregnant rats during periods of organogenesis and on the 4th or 5th day of pregnancy to 34 rats. Examination of the resultant 887 young for congenital defects showed no greater frequency than in controls. These experiments failed to prove that LSD is teratogenic in rats.