The Neuroscientist
December 26, 2025
Kallol Bera, Loren L. Looger, Alex Proekt et al.
5 citations
Ketamine is a unique anesthetic agent that induces dissociative anesthesia, characterized by perceptual detachment, analgesia, and altered states of consciousness. Beyond its widespread use in anesthesia, subhypnotic ketamine dosing has emerged as a rapid-acting antidepressant and a valuable model for probing the neural mechanisms underlying consciousness and neuropsychiatric disorders. At the...
The Neuroscientist
May 25, 2022
Georg Northoff, Deniz Vatansever, Andrea Scalabrini et al.
53 citations
What is the role of the brain's ongoing activity for cognition? The predominant perspectives associate ongoing brain activity with resting state, the default-mode network (DMN), and internally oriented mentation. This triad is often contrasted with task states, non-DMN brain networks, and externally oriented mentation, together comprising a "dual model" of brain and cognition. In opposition to...
The Neuroscientist
September 1, 2017
Selen Atasoy, Gustavo Deco, Morten L. Kringelbach et al.
131 citations
A fundamental characteristic of spontaneous brain activity is coherent oscillations covering a wide range of frequencies. Interestingly, these temporal oscillations are highly correlated among spatially distributed cortical areas forming structured correlation patterns known as the resting state networks, although the brain is never truly at "rest." Here, we introduce the concept of harmonic...
The Neuroscientist
January 4, 2005
Olaf Blanke, Shahar Arzy
468 citations
Folk psychology postulates a spatial unity of self and body, a "real me" that resides in one's body and is the subject of experience. The spatial unity of self and body has been challenged by various philosophical considerations but also by several phenomena, perhaps most notoriously the "out-of-body experience" (OBE) during which one's visuo-spatial perspective and one's self are experienced...
The Neuroscientist
August 1, 2000
J. David Jentsch, Jane R. Taylor, Robert H. Roth
Long-term intake of noncompetitive N-methyl-D-aspartate (NMDA)/glutamate receptor antagonists, such as phencyclidine (PCP), can simulate schizophrenia-like symptomatology in human subjects and can produce aberrant behavior in animals. The behavioral changes produced by PCP in animals have been suggested to model certain primary symptoms of idiopathic psychotic disorders, and the neurobiological...