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Thaddeus Alfonso

3 papers in the library · 1 citation · publishing 2025-2026

Papers

Mindfulness in treatment-seeking adults with comorbid obsessive-compulsive and major depressive disorders: Mediating effects of obsessive beliefs and mental well-being.

Indian Journal of Psychiatry May 1, 2025 Mohammad Asif Sheikh, Thaddeus Alfonso 1 citation

Mindfulness is linked to reduced symptom severity in adults with both obsessive-compulsive disorder (OCD) and major depressive disorder (MDD), but through different pathways. In 60 treatment-seeking adults with comorbid OCD and MDD, mindfulness was significantly associated with lower OCD and MDD symptoms. For MDD, this effect was mediated by reductions in obsessive beliefs and improvements in mental well-being. However, these mediators did not significantly explain mindfulness's effect on OCD symptoms, suggesting that mindfulness works through distinct mechanisms for each condition and that tailored interventions may be needed.

Mindfulness-based exposure and response prevention in individuals with comorbid obsessive-compulsive and major depressive disorders: a randomized controlled trial

Scientific Reports July 15, 2026 Mohammad Asif Sheikh, Thaddeus Alfonso

For adults with both obsessive-compulsive disorder (OCD) and major depressive disorder, a mindfulness-based version of exposure and response prevention (MB-EX/RP) led to greater reductions in OCD symptoms, obsessive beliefs, and improvements in mindfulness and mental well-being compared to standard exposure and response prevention alone. Depressive symptoms improved in both groups, with a larger improvement in the MB-EX/RP group, though the rate of change was similar. Of 54 participants, 40 completed 17 sessions. Gains were maintained at a four-month follow-up, and antidepressant use did not affect results. Integrating mindfulness into exposure-based treatment may improve outcomes for people with these co-occurring conditions.

Mindfulness-Based Interventions to Restore Interpersonal Trust following Betrayal

IntechOpen eBooks May 11, 2026 Puspanjali Borthakur, Thaddeus Alfonso

Betrayal violates trust and can cause lasting psychological harm that conventional apologies and forgiveness may not fully address. This chapter argues that mindfulness-based interventions (MBIs) offer a complementary approach by fostering present-moment awareness, nonjudgmental acceptance, and kindness, which can aid emotional regulation, empathy, forgiveness, and relational resilience. The authors contend that MBIs can be applied in clinical, professional, and social settings as both a therapeutic technique and a relational strategy to restore trust and promote psychological safety after betrayal. The chapter integrates academic concepts, real-life examples, and tested strategies to support this argument.