Frontiers in Physiology
August 10, 2026
Dan Yu, Ye Liao, Jie Li et al.
Propofol, one of the most widely used intravenous anesthetics, is undergoing a transformative identity shift from a purely surgical agent to a potential therapeutic tool for neuropsychiatric disorders. This review synthesizes current evidence on the emerging field of propofol therapeutics, with a focus on its rapid antidepressant, anti-anhedonia, and anxiolytic effects. We first examine...
Frontiers in Physiology
January 23, 2023
Aravind Natarajan
36 citations
We discuss Heart Rate Variability (HRV) measured during mindful breathing meditation. We provide a pedagogical computation of two commonly used heart rate variability metrics, i.e. the root mean square of successive differences (RMSSD) and the standard deviation of RR intervals (SDRR), in terms of Fourier components. It is shown that the root mean square of successive differences preferentially...
Frontiers in Physiology
2023
Aravind Natarajan, Hulya Emir-Farinas, Hao-Wei Su
Introduction: Hypertension is one of the most important, modifiable risk factors for cardiovascular disease. The popularity of wearable devices provides an opportunity to test whether device guided slow mindful breathing may serve as a non-pharmacological treatment in the management of hypertension. Methods: Fitbit Versa-3 and Sense devices were used for this study. In addition, participants...
Frontiers in Physiology
September 2, 2022
Charles Verdonk, Marion Trousselard, Takfarinas Medani et al.
Enhanced body awareness has been suggested as one of the cognitive mechanisms that characterize mindfulness. Yet neuroscience literature still lacks strong empirical evidence to support this claim. Body awareness contributes to postural control during quiet standing; in particular, it may be argued that body awareness is more strongly engaged when standing quietly with eyes closed, because only...
Frontiers in Physiology
February 11, 2020
Thomas A. W. Bolton, Diana Wotruba, Roman Buechler et al.
83 citations
Emerging evidence has attributed altered network coordination between the default mode, central executive, and salience networks (DMN/CEN/SAL) to disturbances seen in schizophrenia, but little is known for at-risk psychosis stages. Moreover, pinpointing impairments in specific network-to-network interactions, although essential to resolve possibly distinct harbingers of conversion to clinically...
Frontiers in Physiology
May 29, 2018
Rohisha Tuladhar, Gyanendra Bohara, Paolo Grigolini et al.
In this paper we emphasize that 1/f noise has two different origins, one compatible with Laplace determinism and one determined by unpredictable crucial events. The dynamics of heartbeats, manifest as heart rate variability (HRV) time series, are determined by the joint action of these different memory sources with meditation turning the Laplace memory into a strongly coherent process while...
Frontiers in Physiology
2018
Brian Key, Deborah J Brown
There is compelling evidence that the "what it feels like" subjective experience of sensory stimuli arises in the cerebral cortex in both humans as well as mammalian experimental animal models. Humans are alone in their ability to verbally communicate their experience of the external environment. In other species, sensory awareness is extrapolated on the basis of behavioral indicators. For...
Frontiers in Physiology
July 4, 2016
Anirban eBhaduri, Dipak eGhosh
Abstract: Abstract: The cardiac dynamics during meditation is explored quantitatively with two chaos-based non-linear techniques viz. multi-fractal detrended fluctuation analysis and visibility network analysis techniques. The data used are the instantaneous heart rate (in beats/minute) of subjects performing Kundalini Yoga and Chi meditation from PhysioNet. The results show consistent...
Frontiers in Physiology
March 25, 2014
Marcelo Demarzo, Jesus Montero-Marin, Phyllis K Stein et al.
The psychological construct of mindfulness refers to an awareness that emerges by intentionally paying attention to the present experience in a non-judgmental or evaluative way. This particular quality of awareness has been associated to several indicators of physical and psychological health, and can be developed using mindfulness-based interventions (MBIs), and therefore MBIs have been...
Frontiers in Physiology
2011
Stephanie L Hawkins
American psychologist and philosopher William James devoted the entirety of his career to exploring the nature of volition, as expressed by such phenomena as will, attention, and belief. As part of that endeavor, James's unorthodox scientific pursuits, from his experiments with nitrous oxide and hallucinogenic drugs to his investigation of spiritualist mediums, represent his attempt to address...