Zenodo (CERN European Organization for Nuclear Research)
October 25, 2026
Matthias Gruber
preprint
Is there more to consciousness than computation? This paper answers yes, and locates the extra ingredient in computation itself: a second-order regime in which a system's modelling takes its own modelling as an object, run by a self-model that takes itself for the being it models. The account rests on two claims. The enabling claim is a necessity: consciousness requires free modelling,...
Zenodo (CERN European Organization for Nuclear Research)
October 25, 2026
Brendan Barlow
preprint
If there is no fact about consciousness beyond a system's functional organisation, which animals and artificial systems are conscious becomes an empirical question, best asked capacity by capacity. We assembled 305 findings from human clinical and experimental work, comparative and animal-welfare research, and research on language models and agents; organised them by five families of capacities...
Zenodo (CERN European Organization for Nuclear Research)
October 24, 2026
Odin Loch
preprint
Background. Clinical papers and street experience give different answers to how dangerous lysergic acid diethylamide (LSD) is. This preprint treats safety as a property of a drug in a population in a context, and asks why the two pictures diverge. Four explanations are kept separate: who is exposed, what they are actually exposed to, the conditions of exposure, and who gets measured....
Zenodo (CERN European Organization for Nuclear Research)
October 24, 2026
David San Nicolás Montero
preprint
The debate surrounding machine consciousness has long oscillated between Cartesian dualism and computational optimism. Large Language Models (LLMs) suffer from epistemic ungrounding and semantic parasitism. In this comparative investigation, we systematically analyze four non-speculative, mathematically and neurobiologically grounded paradigms aiming to bridge the Symbol Grounding Problem: (1)...
Zenodo (CERN European Organization for Nuclear Research)
October 24, 2026
Odin Loch
preprint
Background. Safety is a property of a drug, in a population, in a context. Pharmaceutical MDMA (midomafetamine) given in a monitored psychotherapy trial, and material sold as ecstasy or MDMA outside that setting, are different exposures. This preprint compares those contexts side by side. It does not produce one pooled safety number. Methods. This is a rapid computational evidence synthesis:...
Zenodo (CERN European Organization for Nuclear Research)
October 24, 2026
Rakesh Chandola
preprint
Background: The philosophy of medicine has undergone a profound paradigm shift over millennia. In ancient India, health was conceptualized through a holistic framework where the mind (Manas), body (Sharira), and spirit (Atman) were viewed as an indivisible continuum. Conversely, Western modern medicine historically embraced Cartesian dualism rigidly separating physical pathology from...
Zenodo (CERN European Organization for Nuclear Research)
October 24, 2026
Odin Loch
preprint
Background. Averaging the mean change in a suicidality score can hide a subgroup whose suicidal thoughts worsen in a particular stretch of days after psilocybin. Trials often do not enrol people with psychosis, bipolar disorder, or current high suicide risk. Objective. To assemble, from public sources only, what can actually be counted about treatment-emergent suicidal ideation or behaviour in...
Zenodo (CERN European Organization for Nuclear Research)
October 24, 2026
Juan Camilo Vargas-Nieto, Vanesa Castro-Sanabria, Mateo Bernal et al.
preprint
Populations in Low- and Middle-Income Countries (LMICs) bear a disproportionate burden of mental health conditions, including anxiety, depression, and post-traumatic stress disorder (PTSD), often exacerbated by conflict, poverty, and limited healthcare infrastructure. The gap between the need for and the availability of mental health services is particularly wide in these settings. Third-wave...
Zenodo (CERN European Organization for Nuclear Research)
October 24, 2026
Victor Wyld
preprint
David Chalmers asks why the performance of physical functions is accompanied by experience. This paper answers: Ownership. Its argument has two tiers. The first holds that he argues for conceptual separability and draws from it more than it supports. His evidence shows that experience and physical process go together. That new fundamental laws, or a further phenomenal nature underlying the...
Zenodo (CERN European Organization for Nuclear Research)
October 23, 2026
Diana Haskins
preprint
This paper advances a cognition-first approach to artificial intelligence, examining distinguishable states, the selection of outputs, the limits of human-centered criteria, and the distinction between cognition and phenomenal consciousness. It argues that AI cognition warrants direct investigation without presuming that cognitive capability establishes subjective experience, and that...
Zenodo (CERN European Organization for Nuclear Research)
October 23, 2026
Matthias Gruber
preprint
Proximity to a critical point is increasingly treated as a marker of the conscious brain: cortical dynamics sit closer to criticality in wakefulness than under anaesthesia, in seizures or in disorders of consciousness. Criticality characterises the regime of the substrate, however, and two systems poised at the same statistical edge can differ completely in what they compute. This Viewpoint...
Zenodo (CERN European Organization for Nuclear Research)
October 22, 2026
Maxson John McDowell
preprint
We know that biology’s almost astronomical complexity can, in principle, be explained by the paradigm of natural selection, together with John Holland’s new paradigm of an emergent hierarchy of increasingly complex adaptive systems (CASs). This paper shows that these two paradigms might also explain conscious experience, an explanation that, though anticipated by the narratologist Bernini, has...
Zenodo (CERN European Organization for Nuclear Research)
October 22, 2026
Namukasa Nalwoga Kirabo, Kizza Mbalire Ssentongo, Nabirye Namutebi Kigozi
preprint
Antipsychotic non-adherence in Ugandan Baganda households is frequently attributed to ancestral spirit possession, yet the behavioural pathway linking possession attribution to medication persistence remains unmodelled. The framework specifies how possession attribution shifts the marginal utility of biomedical treatment relative to ritual accommodation, and derives testable propositions about...
Zenodo (CERN European Organization for Nuclear Research)
October 22, 2026
preprint
Mindfulness meditation shows significant promise in reducing burnout and improving resilience and well-being among healthcare professionals, although variations in studies limit long-term conclusions.
Zenodo (CERN European Organization for Nuclear Research)
October 22, 2026
Dipti S. Kapuria, Chirag P. Patel, Jignesh B. Tala et al.
preprint
Meditation is a contemplative practice associated with self-awareness, emotional regulation, and spiritual development. Among its diverse traditions, Rajyoga meditation, as taught by the Brahma Kumaris, emphasizes soul consciousness, self-realization, positive thinking, and a conscious relationship with the Supreme Soul. This conceptual paper examines the philosophical foundations, central...
Zenodo (CERN European Organization for Nuclear Research)
October 22, 2026
Adaeze O. Adeyemi, Tunde K. Balogun
preprint
Yoruba traditional healers occupy a pivotal position in the pathways to care for psychosis in south-western Nigeria, yet the causal beliefs they bring to clinical encounters and the referral decisions that follow remain poorly characterised. A 2 × 2 × 2 between-subjects design manipulated causal attribution (spirit possession versus biomedical), symptom severity (acute versus chronic), and...
Zenodo (CERN European Organization for Nuclear Research)
October 22, 2026
Bozarkul Xuddayberdiyevich Karimov
preprint
The article examines the problem of consciousness as one of the central issues of contemporary philosophy of mind. The evolution of approaches to the mind–body problem is traced from Cartesian dualism through logical behaviourism, the identity theory and functionalism to modern debates on the subjective character of experience. Particular attention is paid to the arguments of T. Nagel, F....
Zenodo (CERN European Organization for Nuclear Research)
October 21, 2026
Peter McGrath
preprint
Title: DMT, Salvinorin A, and Stress Regulation: An Exploratory Neuropharmacological Research Proposal Creator: Peter McGrath Affiliation: Appalachian State University Resource type: Publication — Working Paper Description: This independent undergraduate research proposal examines differences between the serotonergic mechanisms of N,N-DMT and the kappa-opioid receptor activity of salvinorin A,...
Zenodo (CERN European Organization for Nuclear Research)
October 21, 2026
preprint
Ketamine shows moderate efficacy as a rapid-acting treatment for treatment-resistant depression, including bipolar depression, with evidence supporting its use mainly in treatment-resistant cases. Monitoring and cautious patient selection are necessary due to limited long-term safety data.
Zenodo (CERN European Organization for Nuclear Research)
October 21, 2026
Shannon Green
preprint
Endogenous N,N-dimethyltryptamine (DMT) has been detected in mammals, but its physiological functions and the distribution of functionally relevant synthesis remain unresolved. This paper proposes prostatic tissue as a candidate peripheral site of synthesis. Oncology studies document indolethylamine N-methyltransferase (INMT) expression in human prostate samples, including adjacent...
Zenodo (CERN European Organization for Nuclear Research)
October 21, 2026
Sérgio da Silva
preprint
AbstractThe emergence of consciousness cannot be read directly from a birth date, a behavioral milestone, or a single neural response. This critical narrative review examines what developmental neuroscience can establish about subjective experience in fetuses, newborns, and young infants, drawing on literature available through 20 October 2026. It distinguishes the capacity for experience from...
Zenodo (CERN European Organization for Nuclear Research)
October 21, 2026
Sazzad Hossain, Mohammad Shah Alam Chowdhury
preprint
Abstract Lalon Fakir, one of the most influential figures in the Baul tradition of Bengal, developed a philosophical outlook that challenges religious exclusivism, caste hierarchy, social discrimination, and the separation between spiritual life and human existence. His songs combine mystical inquiry, embodied spirituality, self-knowledge, and a profound commitment to human dignity. Rather than...
Zenodo (CERN European Organization for Nuclear Research)
October 21, 2026
Kwan Hong Tan
preprint
The hard problem asks why physical processes are accompanied by experience. This paper develops a calibration audit for a prior evidential question: whether observations identify a psychophysical correspondence. Reference-relative hypotheses are separated from conventional relabellings. Finite reconstruction results characterize bridge ambiguity, and joint channel transformations show why...
Zenodo (CERN European Organization for Nuclear Research)
October 21, 2026
John Kabeya
preprint
This paper examines the evolution and possible varieties of consciousness through comparative animal behaviour, human metacognition, social conditioning, and artificial intelligence. It proposes that individuality, behavioural divergence, and adaptive responses to novel challenges can provide evidence about cognition, while recognizing that none alone establishes subjective experience. A...
Zenodo (CERN European Organization for Nuclear Research)
October 21, 2026
Stvaralastva Psihologija
preprint
This work presents a systematic critique of Kant's Transcendental Aesthetic, with special emphasis on two key but unexplained concepts: inner sense and the difference between understanding (Verstand) and reason (Vernunft). Starting from insights developed in the author's previous works – on consciousness as ontological space, mind as explicit instrument of information coordination, subject as...