Neural tissue contains no single executive that inspects every available action, yet an organism can maintain alternatives, commit to one action, monitor its consequences, and alter later behavior. This paper proposes a multiscale model in which learned synaptic and dendritic states make cellular transitions criterion-sensitive; excitation, inhibition, and disinhibition change time-varying...
The Effects of Yoga, Meditation, and Breathing Techniques on Mental Health: A Systematic Literature Review and Proposal for an Integrated Neurosomatic Mental Health Model Mental health problems associated with stress, anxiety, and reduced psychological well-being have become increasingly prevalent worldwide, highlighting the need for innovative and integrative approaches in mental health care...
of the Review This anatomical review subjects Melo and Roca's (2026) preprint On Cognitive Continuity to systematic structural analysis. The paper advances a relational account of the persistent re-emergence of coherent symbolic patterns in longitudinal human–LLM interaction, carefully distinguishing the phenomenon from memory retention, personalization, roleplay, and autonomous consciousness....
Martin Heidegger distinguishes between calculative thinking, which computes possibilities and moves from one prospect to another, and meditative thinking, which contemplates the meaning disclosed through what is encountered. This paper argues that Heidegger’s distinction can be interpreted as identifying two experientially recognizable modes of mind: calculative seeking and meditative...
Post-Perturbation Integrative Neuroplasticity (PPIN) is a descriptive framework for sustained, non-pathological cognitive reorganization following significant perturbation events such as severe trauma, near-death experiences, or extreme stress. Unlike acquired savant syndrome, which typically produces narrow, domain-specific skill emergence, PPIN describes broad cross-domain integration,...
Modern smartphone technology has effectively eliminated the brief, empty intervals of daily life—such as waiting for an elevator, standing in line, or sitting at a red light. This paper defines this phenomenon as the loss of "micro-boredom." While historically dismissed as trivial, these transient periods of understimulation serve crucial cognitive functions. This article explores how the...
Martin Heidegger’s distinction between calculative and meditative thinking can be read as a contrast between two orientations of consciousness: a seeking orientation that approaches what appears through projects and possibilities, and a receptive orientation that allows what appears to remain present. That distinction, developed in a companion paper, is powerful but coarse. It names two poles...
Olanzapine shows effectiveness in preventing psychotic relapse in cannabis-induced psychosis and has fewer extrapyramidal side effects compared to haloperidol, though no direct superiority in symptom management was observed.
Zenodo (CERN European Organization for Nuclear Research)July 17, 2026Bartosz Niciński, Magdalena Kloc, Ewa Wiench, Natasza Millan, Aleksandra Blicharz, Wojciech Kozdraś, Lidia Kozaczko, Gabriela Szewczyk, Elżbieta Bukowczan, Alicja Zając, Damian Broda, Alicja Benecka
preprint
Major depressive disorder is a highly burdensome psychiatric condition worldwide, and many patients do not achieve full remission after standard monoaminergic antidepressant treatment. This has contributed to growing interest in rapid-acting antidepressant interventionstargeting neurobiological pathways beyond traditional serotonin, norepinephrine, and dopamine mechanisms. This review...
This is an updated version of the previous preprint. This version includes revisions, refinements, and improvements to the theoretical framework and presentation of the proposed model of consciousness. This paper proposes that consciousness arises neither from pure information processing nor from pure biological need, but from their interaction. We formalize this intuition in a mathematical...
This article develops a theological account of attention as a central dimension of Christian discipleship and spiritual formation. It argues that attention is neither psychologically neutral nor merely a matter of personal productivity, but a moral and spiritual practice through which human desire, perception, memory, and action are gradually shaped. Drawing upon biblical theology, Christian...
Background: For millennia, mantra-based meditation practices, including Transcendental Meditation (TM), have been central to various contemplative traditions. In recent decades, these techniques have become a focus of rigorous scientific investigation, primarily within the field of stress medicine. Aim: This paper aims to synthesise the current evidence on the physiological and psychological...
Abstract: The philosophical tradition has been preoccupied with the concept of the mind throughout various intellectual traditions. Indian philosophy gives us a great insight of mind and its workings. The classical schools of Nyāya and Vaiśeṣika give a distinctive account of mind (manas) as an internal organ mediating between the self, the senses and external objects. Unlike materialistic...
Nursing is a highly demanding profession that exposes staff to sustained occupational stress, emotional labor, shift work, and high patient-care expectations. These pressures can contribute to burnout, decreased resilience, and poorer psychological well-being. Mindfulness-Based Stress Reduction (MBSR) has received increasing attention as a feasible intervention to support nurses’ mental health...
This methodological perspective addresses a recurring inferential problem in the study of artificial intelligence and human consciousness: observable manifestations are often treated as sufficient evidence of deeper latent properties. Fluent self-description may be interpreted as subjectivity, repeated behavior as an internal commitment, stable output as intrinsic direction, cognitive access as...
Abstract: One of India’s most lasting intellectual and spiritual traditions is yoga. Yoga, which has its roots in the Sanskritic tradition of ancient India, offers a comprehensive philosophy of life that goes beyond its modern understanding as a discipline of physical practice. The goal of yoga is to harmonise the body, mind, and awareness. It is derived from the Sanskrit linguistic root yuj,...
Among the Tamil mystic poets of the eighteenth century, Thayumanavar has a distinctive position, and his songs are valuable poetic compositions. They are the records of his spiritual experience. The songs embody the philosophical tenets of Saiva Siddhanta, the manifold emotions of human existence, and the soul's benevolent journey towards the realisation of the divine. Thayumanavar employs...
Dissociative psychoactive substances (such as ketamine and PCP) present a challenge to standard models of altered states of consciousness. Unlike classical hallucinogens which enrich or distort conscious content, dissociatives induce a peculiar fragility in the construction of one’s world-model – a breakdown of the high-level coherence that ordinarily binds perception, selfhood, and meaning....
This article critically reviews the encounter between selected existential philosophies and enactive approaches to cognition. “Classical existentialism” functions as a retrospective review category, while enactivism is treated through the influential but contested distinction among autonomy-centred, sensorimotor, and radical approaches. The review distinguishes documented influence, mediated...
Background: In digital and social ecosystems with a high degree of collectivism like Japan, user participation metrics and interpersonal interaction obligations often trigger massive cognitive and emotional pressure. The concept of Ohitorisama (the behavior of consciously celebrating solo activities) has emerged as an antithesis to these exhausting social obligations. This phenomenon indicates...
This paper proposes treating N-methyl-D-aspartate (NMDA) receptor modulation as a single bidirectional pharmacological axis, with ketamine (an NMDA antagonist) and glycine-site enhancers such as sarcosine and D-serine (NMDA agonists/enhancers) sitting at opposite poles. Both directions have documented human trial evidence, but in separate literatures — ketamine in anesthesia and depression...
This paper aims to analyze the concepts mobilized by Augustine in De Trinitate, as well as to address the arguments presented to justify the nature of the mind (mens). Furthermore, I argue that, within this work, self-knowledge functions as a sufficient epistemological foundation for the defense of the mind’s incorporeity. In this context, I examine the roles of memory and will as constitutive...
Mindfulness-based interventions have demonstrated benefits for emotional regulation, psychological resilience, and well-being, yet the structural mechanisms through which mindfulness produces sustained transformation remain insufficiently articulated. Existing explanations—attention regulation, body awareness, decentring, emotion regulation, neuroplasticity—are typically presented as parallel...
A study published in Physics of Life Reviews provides a culmination and review of the development over the past 20 years of the theory that "orchestrated objective reduction" (Orch OR) occurring within microtubules in brain neural networks forms consciousness. It asserts that the source of conscious experience is not classical synaptic computation, but coherent quantum processes occurring...
The sense of agency (SoA) and the sense of metacognitive presence (SoP) — the felt engagement of the self-monitoring system — are typically treated as convergent markers of intact conscious experience: both high in normal function, both degraded in dissociative states. Here I propose that they are, in fact, two dissociable axes of a single predictive mechanism that diverge in antiphase under...