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Journal of Psychoactive Drugs

ISSN 0279-1072, 2159-9777

415 papers in the library · 13,118 citations · publishing 1976-2026

Papers

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Treatment of alcoholism using psychedelic drugs: a review of the program of research.

Journal of Psychoactive Drugs 1998 M Mangini 107 citations

Following Albert Hofmann's discovery of LSD's psychoactive properties in 1943, and previous to their scheduling as controlled substances, the psychedelic drugs were widely studied--six international conferences and hundreds of papers discussed their potential therapeutic usefulness. The observation that the frightening experience of delirium tremens sometimes led alcoholics to moderate their...

DOI: 10.1080/02791072.1998.10399714 (opens in new tab) Full text (opens in new tab) Psychedelic therapy LSD Treatment Hallucinogen therapy Mind-altering drug therapy +16

Embalming fluid-soaked marijuana: new high or new guise for PCP?

Journal of Psychoactive Drugs 1998 J A Holland, L Nelson, P R Ravikumar et al.

A growing trend of smoking marijuana soaked in what is purported to be embalming fluid has been reported in the literature since the mid-1980s. This article describes several cases of intoxication, gives regional epidemiological data on this phenomenon, and includes current nomenclature. The authors also analyze a sample of fluid said to be embalming fluid and discover PCP (phencyclidine) and...

Hallucinogens, serotonin and obsessive-compulsive disorder.

Journal of Psychoactive Drugs 1998 P L Delgado, F A Moreno

The serotonin (5-HT) neurotransmitter system has been implicated in the pathophysiology of several neuropsychiatric disorders, especially obsessive-compulsive disorder (OCD). Blockade of 5-HT reuptake appears to be an important initial neurobiological event in the therapeutic mechanism of action of antiobsessional drugs. However, for reasons that continue to be poorly understood, clinical...

Ketamine Psychedelic Therapy (KPT): A Review of the Results of Ten Years of Research

Journal of Psychoactive Drugs June 1, 1997 Evgeny Krupitsky, Alexander Grinenko 241 citations

Ketamine is a prescription drug used for general anesthesia. In subanesthetic doses, it induces profound psychedelic experiences and hallucinations. The subanesthetic effect of ketamine was the hypothesized therapeutic mechanism in the authors' use of ketamine-assisted psychotherapy for alcoholism. The results of a controlled clinical trial demonstrated a considerable increase in efficacy of...

Set, Setting, and Matrix

Journal of Psychoactive Drugs June 1, 1997 Betty Grover Eisner 129 citations

The future use of psychedelics as an aid to therapeutic change is bound to come. The best source of information on how to use these extraordinary drugs is clearly a detailed description of the successes (and failures) of those researchers who have used these compounds to bring curative, creative and growth-potentiating experiences to their patients. A study of their work is recommended in order...

Bufo toads and bufotenine: fact and fiction surrounding an alleged psychedelic.

Journal of Psychoactive Drugs 1996 T Lyttle, D Goldstein, J Gartz 84 citations

This paper investigates the supposedly psychedelic Bufo toad and the allegedly psychedelic drug bufotenine, which is contained in the skin and glands of this toad. The bufo toad has held a place in human mythologies and medicines worldwide since archaic times. Used by ancient peoples for a variety of purposes, its most spectacular effects, according to lore, involve magical and shamanic or...

Illicit use of ketamine in Scotland.

Journal of Psychoactive Drugs 1996 Phil Dalgarno, David Shewan

Semistructured interviews were carried out with 20 illicit users of ketamine in Scotland. Participants had used a wide range of illegal drugs. Scottish drug agencies reported limited contact with ketamine users; however, subjects were knowledgeable regarding the licit purpose of ketamine, its effects, and its legal status. Ketamine was usually obtained through diversion from legitimate sources....

Salvia divinorum and the unique diterpene hallucinogen, Salvinorin (divinorin) A.

Journal of Psychoactive Drugs 1994 Leander J. Valdés 147 citations

Salvia divinorum is a vision-inducing mint used by the Mazatec people of Oaxaca, Mexico. It is grown in California and other parts of the United States where it is employed as a legal hallucinogen. Traditional opinion has been that the plant has mild psychotropic activity, at best. However, when ingested in the correct manner, it is quite powerful. The fresh leaves are chewed as a quid and kept...

Psychedelic and Entactogenic Drugs in the Treatment of Depression

Journal of Psychoactive Drugs 1994 Thomas J. Riedlinger, June E. Riedlinger 39 citations

CNS deficiency of 5-hydroxytryptamine (serotonin) has been implicated as a biochemical basis in some forms of depression. Existing drug modalities for treating depression include some with serotonergic effects. Studies suggest that psychedelic drugs are also serotonergic. This may indicate a role for psychedelics in the treatment of depression. Such treatment has already been attempted using...

Wasson's Alternative Candidates for Soma

Journal of Psychoactive Drugs April 1, 1993 Thomas J. Riedlinger 7 citations

Citing recently published challenges to R. Gordon Wasson's identification of Vedic soma as the psychoactive mushroom Amanita muscaria (fly-agaric), this article reviews unpublished letters by Wasson in which he considered and rejected other psychoactive plants as candidates, including the mint Lagochilus inebrians, Convolvulaceae (morning glory) seeds, the fungal parasite Claviceps purpurea...

DOI: 10.1080/02791072.1993.10472245 (opens in new tab) Mushroom Traditional medicine Toxicology

New Age Seekers: MDMA Use as an Adjunct to Spiritual Pursuit

Journal of Psychoactive Drugs July 1, 1991 Lynne Watson, Jerome Beck 32 citations

The use of MDMA as an adjunct to spiritual pursuit among New Ager seekers is examined. These study respondents indicated that social worlds greatly influenced which qualities of the MDMA experience were most pursued and valued. In contrast to recreationally oriented respondents, who saw minimal long-term benefits accruing from MDMA use, New Agers typically believed that carefully planned...

Human hallucinogenic drug research in the United States: a present-day case history and review of the process.

Journal of Psychoactive Drugs 1991 R J Strassman

Legitimate human research with hallucinogenic drugs, although of great theoretical and practical interest, involves daunting regulatory hurdles that have discouraged investigators from attempting such work. Using the example of the author's own application for and receipt of federal permission to administer N,N-dimethyltryptamine (DMT) to humans, this article reviews the application process,...

DOI: 10.1080/02791072.1991.10472572 (opens in new tab) Humans Hallucinogens Legislation, drug United states

Sociopsychotherapeutic Functions of Ayahuasca Healing in Amazonia

Journal of Psychoactive Drugs 1989 Walter Andritzky 59 citations

The social and psychotherapeutic functions of healing rituals with ayahuasca among Amazonian groups are examined, and their healing effectiveness is explained in terms of Western scientific and sociopsychotherapeutic perspectives. The article includes an overview of the preparation and application of ayahuasca, the symbolic adaptations to the process of social change, the role of singing, the...

DOI: 10.1080/02791072.1989.10472145 (opens in new tab) Ayahuasca Vision Transcendental number Psychotherapist +1

Shamans, Sacraments, and Psychiatrists

Journal of Psychoactive Drugs 1989 Gary Bravo, Charles S. Grob 38 citations

This article reviews the role of psychedelic drugs as potential tools for psychiatric research and practice. The decline in the utilization of these substances is linked to social reactions, which led to psychedelics being scheduled as controlled substances and consequently unavailable for human research. Three different paradigms for the use of psychedelics in psychiatry are reviewed: the...

Shamanism and Altered States of Consciousness: An Introduction

Journal of Psychoactive Drugs 1989 Marlene Dobkin De Rios, Michael Winkelman 37 citations

In this article, the issue of shamanism and altered states of consciousness (ASC) is reviewed from a cross-cultural and multidisciplinary perspective. It is suggested that in spite of considerable differences in the uses of these terms, there are conceptual and empirical grounds for distinction among different types of trance practitioners. The authors argue that shamanism is a cultural...

The sacred journey in dynastic Egypt: shamanistic trance in the context of the narcotic water lily and the mandrake.

Journal of Psychoactive Drugs 1989 W Emboden 32 citations

Contemporary reference to the role of water lilies and mandrakes (Nymphaea and Mandragora, respectively) in ancient Egyptian healing, and subsequent research on the iconography of the water lily in Mayan shamanistic ritual, suggest the possible importance of these plants as adjuncts to shamanistic healing in dynastic Egypt. Although the usual interpretation of the water lily and the mandrake...

LSD and Creativity

Journal of Psychoactive Drugs 1989 Oscar Janiger, Marlene Dobkin De Rios 29 citations

The effects of lysergic acid diethylamide (LSD) on creativity were examined in a unique experiment in the late 1950's. In this project, artists were asked to draw and paint a Kachina doll both prior to and one hour after the ingestion of LSD. Evaluations of these artistic productions were analyzed by a professor of art history in order to investigate the impact of LSD on artistic creativity....

The nature of the shamanic state of consciousness: a review.

Journal of Psychoactive Drugs 1989 P A Wright 20 citations

A review of the literature suggests that a common psychobiological process is associated with various altered states of consciousness (ASC) utilized by shamans, meditators, and mediums. However, the shamanic state of consciousness (SSC) can be differentiated physiologically from possession trance states. The psychophysiological literature on different types of trances and on seizure conditions...

What has really been learned about shamanism?

Journal of Psychoactive Drugs 1989 R Noll 11 citations

Within anthropology, investigations of shamans and their altered states of consciousness have followed some of the prescriptive problems inherited from the discipline of psychology, coloring the assumptions and perspectives of students of shamanism. These inherited problems include the following: conscious/volitional versus unconscious/involuntary mentalisms; contentual objectivism versus...

Jungian shamanism.

Journal of Psychoactive Drugs 1989 H A Senn 4 citations

The literature on shamanism generally describes a specially gifted individual who is able to contact and communicate with a realm where spirit beings offer wisdom and help, and who actively transmits this knowledge to others. There seem to be approximately five features that define shamanism: the necessity of a "call"--an illness or accident that signifies the necessity of the individual to...

A philosophical inquiry to include trance in epistemology.

Journal of Psychoactive Drugs 1989 H Wautischer 3 citations

In a state of voluntary trance or meditation, the perception of reality appears to extend beyond the usual spatial and temporal boundaries that are normally perceived by the sense organs. It is argued that the problems of validity and reliability of trance experiences for scientific discourse are in principle no different than the problems associated with ordinary perception. The shift in early...