Neurology Bulletin
March 23, 2026
Azat R. Asadullin, Elvina A. Akhmetova, Ilia S. Efremov et al.
BACKGROUND: Substance use disorders remain a global public health problem. In recent decades, the drug market has undergone substantial changes, with traditional drugs increasingly replaced by new psychoactive substances characterized by high toxicity and strong addictive potential. Their distribution via the Internet and social media impedes control and increases risks to public health. AIM:...
International Journal of Transpersonal Studies
July 1, 2014
Eli Kolp, Harris L. Friedman, Evgeny Krupitsky et al.
53 citations
Meant to be an authoritative guide for psychiatrists and others interested in understanding and applying ketamine psychedelic psychotherapy (KPP), this paper focuses on its pharmacology, phenomenology, and clinical applications. Ketamine is a dissociative anesthetic widely used by physicians and veterinarians in the United States. In addition to its anesthetic and dissociative properties,...
Journal of Psychoactive Drugs
March 1, 2007
Evgeny Krupitsky, Andrei M. Burakov, Igor Dunaevsky et al.
176 citations
A prior study found that one ketamine-assisted psychotherapy session was significantly more effective than active placebo in promoting abstinence (Krupitsky et al. 2002). In this study of the efficacy of single versus repeated sessions of ketamine-assisted psychotherapy in promoting abstinence in people with heroin dependence, 59 detoxified inpatients with heroin dependence received a...
International Journal of Transpersonal Studies
2007
Eli Kolp, M. Scott Young, Harris L. Friedman et al.
44 citations
Ketamine, a dissociative anesthetic commonly used by US physicians, has recently been shown to be a powerful anti-depressant and is also capable of eliciting transpersonal experiences that can be transformative. Although currently approved in the US only for use as an anesthetic, physicians there can legally prescribe it off-label to treat various psychological/ psychiatric problems and it has...
Journal of Substance Abuse Treatment
December 1, 2002
Evgeny Krupitsky, Andrey Burakov, Tatyana N. Romanova et al.
240 citations
Seventy detoxified heroin-addicted patients were randomly assigned to one of two groups receiving ketamine psychotherapy (KPT) involving two different doses of ketamine. The patients of the experimental group received existentially oriented psychotherapy in combination with a hallucinogenic ("psychedelic") dose of ketamine (2.0 mg/kg im). The patients of the control group received the same...
Journal of Psychoactive Drugs
June 1, 1997
Evgeny Krupitsky, Alexander Grinenko
241 citations
Ketamine is a prescription drug used for general anesthesia. In subanesthetic doses, it induces profound psychedelic experiences and hallucinations. The subanesthetic effect of ketamine was the hypothesized therapeutic mechanism in the authors' use of ketamine-assisted psychotherapy for alcoholism. The results of a controlled clinical trial demonstrated a considerable increase in efficacy of...