Psychopathology
March 27, 2026
Xiaoran Ding, Yaping Wu, Juan Yang et al.
1 citation
Ketamine has emerged as a promising rapid-acting antidepressant with distinct advantages for the treatment of treatment-resistant depression (TRD). Its therapeutic effects are mediated through multi-target modulation of the glutamatergic system. Unlike conventional antidepressants, ketamine exerts a markedly faster onset of action; however, its long-term safety profile and potential risk of...
Psychopathology
January 1, 2026
Bettina Magnolia Löfs, Andreas Rosén Rasmussen
1 citation
The current definition of hallucinations as perception-like experiences has been criticized for neglecting their experiential character and context. This study examined the phenomenology of auditory verbal hallucinations (AVHs) and visual hallucinations (VHs) in schizophrenia and their relation to other psychopathology, particularly basic self-disorders. Twenty patients with...
Psychopathology
January 1, 2026
Valerio Ricci, Massimiliano Aragona, Giuseppe Maina et al.
1 citation
Healthcare professionals encounter challenges in discerning endogenous and exogenous, drug-related, psychopathological phenomena. This study aimed to explore qualitative differences between hallucinations in schizophrenia and two forms of substance-related psychosis. These are substance-induced psychosis (SIP), which has an acute onset and is usually transient, and substance-related persistent...
Psychopathology
January 1, 2026
Tatiana Baxter, Sohee Park
1 citation
Felt presence (FP) is the experience that another entity is present in one's proximal environment, despite no sensory evidence. Occurrence of FP is linked to psychosis risk, but qualities of FP in the context of psychosis are not well understood. We conducted an online, exploratory survey assessing qualities of FP in relation to psychosis risk in the general population. Three hundred and...
Psychopathology
August 18, 2025
Evan J. Kyzar, George H Denfield, Jasper Feyaerts et al.
1 citation
Dynamical systems theory (DST) has recently gained traction as a framework to describe and predict the progression of psychopathology. However, a number of challenges to the application of DST to psychopathology have arisen, including the heterogeneity of symptom measures and the lack of theoretical underpinnings to describe the temporal unfolding of psychiatric illnesses. In this article, we...
Psychopathology
January 1, 2024
Daniel Nischk, Rico Gutschmidt
1 citation
Spiritual, metaphysical, or eschatological elements in delusions (SMEDs) are frequent and often subjectively regarded as profound transformational experiences, similar to mystical experiences. This study aimed (1) to explore how SMEDs are experienced and in which aspects they are similar to mystical experiences and (2) to investigate how individuals make sense of SMED. Seven participants were...
Psychopathology
January 1, 2024
George H Denfield, Evan J. Kyzar
1 citation
Subjective experience is central to the nature of mental illness, yet it has not played a central role in most empirical approaches to psychopathology. While phenomenological perspectives in psychiatry have seen a recent resurgence, there remains a need for more detailed models of psychopathological processes based on explicit phenomenological and enactive foundations. We present a framework...
Psychopathology
May 19, 2026
Barbara Kariž, Mads Gram Henriksen, Borut Škodlar
There is a growing need to translate insights from phenomenological psychopathology into psychotherapeutic practice. Phenomenology offers a deeper understanding of the lived experience of psychosis, and this understanding can render psychotherapy more individualized, empathically attuned, and recovery-oriented by attending to experiential dimensions that conventional, symptom-focused approaches...
Psychopathology
April 27, 2026
Mads Gram Henriksen, Håvard Hovstad, Helena Cobanovic et al.
The Inventory of Psychotic-Like Anomalous Self-Experiences (IPASE) was developed as an easy-to-use, self-report measure of self-disorders. Self-disorders are subtle, trait-like, non-psychotic anomalous self-experiences that are traditionally assessed by trained raters using a semi-structured clinical interview, such as the Examination of Anomalous Self-Experience (EASE). Whether self-disorders...
Psychopathology
February 2, 2026
Riccardo Poggioli, Giovanni Stanghellini
This paper proposes a critical expansion of phenomenological psychopathology of the individual to explicitly integrate the collective dimension. In order to accurately describe the scenario of collective life, and its relationship with the psychology and psychopathology of individual existences, we propose two moves: (1) A shift of focus from society (which denotes an organized aggregate of...
Psychopathology
January 1, 2026
Elisavet Pappa, Nichola Raihani, Vaughan Bell
Delusions frequently involve strong beliefs about, or interactions with, illusory social agents. Although such agents have been systematically described in hallucinations, few studies have investigated their nature and identity in delusions. We identified 205 electronic mental health records describing the content of delusions from the Clinical Record Interactive Search platform at South London...
Psychopathology
January 1, 2025
Matteo Ballabio, Giovanni Stanghellini
In recent times, adolescents with severe forms of psychopathology that do not unambiguously fit into a precise diagnostic category have come to clinical observation. The diagnoses attributed to these young patients range from borderline personality disorder, to affective disorders, ADHD, and others. These diagnoses are mainly based on behavioural abnormalities (e.g., social withdrawal,...
Psychopathology
June 18, 2026
Julia G. Lebovitz, Sohee Park
Introduction: Alterations in emotional experiences have been demonstrated in depersonalization-derealization disorder (DPD), typically highlighting a blunting of emotions and decreased ability to recognize and name emotions (i.e., alexithymia). However, less research has focused on how individuals with depersonalization experiences embody emotion states. Therefore, the present study...
Psychopathology
June 15, 2026
Ary Gadelha, Bernardo Haguiara, Pedro Gabriel Lorencetti et al.
Contemporary psychiatry has advanced by decomposing behavior into discrete constructs, improving reliability but fragmenting conceptual foundations. Excessive comorbidity, blurred diagnostic boundaries, and the reification of operational criteria have created a gap between empirical data and the understanding of mental life as a coherent, lived whole - the modern paradox of "more data, less...
Psychopathology
May 21, 2026
Pavan S Brar, Elizabeth Pienkos, Gil Grunfeld et al.
An important feature of contemporary phenomenological psychopathology is the development of explanatory accounts, constructed at the level of first-person experience, for why certain phenomena appear in a psychiatric condition. Termed phenomenological explanation, this approach to explanation is intended to uniquely contribute to diagnostic classification and etiology. Despite its promise for...
Psychopathology
May 4, 2026
Paul Goldsmith
Delusions can be strikingly selective: individuals may hold highly elaborated, unshakeable beliefs in one domain while remaining otherwise cognitively intact. Models emphasising dopaminergic salience or belief-updating failures account for the intensity and persistence of delusions but struggle to explain their circumscribed nature. This paper develops a conceptual framework that complements...
Psychopathology
November 12, 2025
The Role of Interoception in Felt Presence and Psychosis Risk.
Psychopathology
September 25, 2025
Multimodal Hallucinations in Muslim Patients with Severe Psychotic Disorders: The Entity Experience Revisited.
Psychopathology
January 1, 2024
Joke C Van Nieuw Amerongen-Meeuse, Arjan W Braam, Gerlise Westerbroek et al.
Little is known about types of religious/spiritual (R/S) struggles with regard to various diagnostic groups in mental health care. The current qualitative study aims to give an impression of R/S struggles as observed in six diagnostic groups in clinical mental health care. Inductive thematic content analysis was applied to 34 semi-structured interviews. The interviews were performed among (day)...
Psychopathology
April 24, 2019
Towards a Phenomenology of Self-Patterns in Psychopathological Diagnosis and Therapy.
Psychopathology
January 1, 2019
Paul H Lysaker, Giancarlo Dimaggio, Jay A Hamm et al.
Disturbances in first person experience is a broadly noted feature of schizophrenia, which cannot be reduced to the expression of psychopathology. Yet, though categorically linked with profound suffering, these disturbances are often ignored by most contemporary treatment models. In this paper, we present a model, which suggests that deficits in metacognition and their later resolution...
Psychopathology
January 1, 2018
Andrea Raballo, Antonio Preti
Self-disorders are temporally persisting, experiential anomalies of subjective experiences that index liability to schizophrenia. They impact on the temporal unfolding of concomitant, diagnostic symptoms and can be suitably characterized through the Examination of Anomalous Self Ex periences (EASE). Capitalizing on the results of a recent longitudinal study, we explored the relevant patterns of...
Psychopathology
January 1, 2018
Tor Gunnar Værnes, Jan Ivar Røssberg, Paul Møller
Basic self-disturbance (BSD) is proposed to constitute the clinical core of schizophrenia spectrum disorders, including prodromal states and schizotypy. Anomalous self-experiences (ASEs) are suggested as phenotypic variants of BSD, representing markers of schizophrenia vulnerability. However, ASEs are not restricted to the schizophrenia spectrum, but may also occur in non-psychotic states like...
Psychopathology
January 1, 2014
Lampros Perogamvros
Philosophers, psychiatrists and neuroscientists have all expressed interest in and formulated hypotheses on the nature of hallucinations, but no sufficient integration of these models exists to this date. The objective of this article is to present a neurophilosophical model of psychosis linking the neurobiology with the phenomenology of hallucinations and delusions. It is proposed that...
Psychopathology
January 1, 2005
Benedetto Farina, Maurizio Ceccarelli, Massimo Di Giannantonio
The French psychiatrist Henri Ey developed his organo-dynamic theory of the mind function and consciousness 50 years ago incorporating Hughling Jackson's thinking, along with psychiatric and philosophical theorizations by Janet and Bergson. This model has not received the attention it deserved, but recent advances in neuroscience rekindled interest for Ey's theory. By overcoming the Cartesian...