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Matthew E Larkum

5 papers in the library · 109 citations · publishing 2019-2025

Papers

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Does neural computation feel like something?

Frontiers in Neuroscience 2025 Albert Gidon, Jaan Aru, Matthew E Larkum 1 citation

Artificial neural networks are becoming more advanced and human-like in detail and behavior. The notion that machines mimicking human brain computations might be conscious has recently caused growing unease. Here, we explored a common computational functionalist view, which holds that consciousness emerges when the right computations occur-whether in a machine or a biological brain. To test...

An integrative, multiscale view on neural theories of consciousness.

Neuron May 15, 2024 Johan F. Storm, P Christiaan Klink, Jaan Aru et al. 108 citations

How is conscious experience related to material brain processes? A variety of theories aiming to answer this age-old question have emerged from the recent surge in consciousness research, and some are now hotly debated. Although most researchers have so far focused on the development and validation of their preferred theory in relative isolation, this article, written by a group of scientists...

The feasibility of artificial consciousness through the lens of neuroscience.

Trends in Neurosciences December 1, 2023 Jaan Aru, Matthew E Larkum, James M Shine

Interactions with large language models (LLMs) have led to the suggestion that these models may soon be conscious. From the perspective of neuroscience, this position is difficult to defend. For one, the inputs to LLMs lack the embodied, embedded information content characteristic of our sensory contact with the world around us. Secondly, the architectures of present-day artificial intelligence...

A thalamocortical substrate for integrated information via critical synchronous bursting.

Proceedings of the National Academy of Sciences of the United States of America November 14, 2023 Brandon R Munn, Eli J Müller, Jaan Aru et al.

Understanding the neurobiological mechanisms underlying consciousness remains a significant challenge. Recent evidence suggests that the coupling between distal-apical and basal-somatic dendrites in thick-tufted layer 5 pyramidal neurons (L5PN), regulated by the nonspecific-projecting thalamus, is crucial for consciousness. Yet, it is uncertain whether this thalamocortical mechanism can support...

Coupling the State and Contents of Consciousness

Frontiers in Systems Neuroscience August 30, 2019 Jaan Aru, Mototaka Suzuki, Renate Rutiku et al.

One fundamental feature of consciousness is that the contents of consciousness depend on the state of consciousness. Here, we propose an answer to why this is so: both the state and the contents of consciousness depend on the activity of cortical layer 5 pyramidal (L5p) neurons. These neurons affect both cortical and thalamic processing, hence coupling the cortico-cortical and thalamo-cortical...