Background: Holding a relevant ritualistic and ethnomedicinal value among the Mesoamerican tribes, Tagetes lucida Cav. has recently seen its uses being translated into Western communities, primarily for recreational ends, given its psychoactivity. Despite the new popularity resurgence of entheogens, the available data concerning this plant’s pharmacological and safety profile remain scarce...
Conventionally used for its stimulant, empathogenic and entactogenic effects, 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) is one of the most commonly used psychoactive drugs, specifically among young adults and in nightlife and recreational party contexts. Often perceived as a safe drug, MDMA can display an array of toxic effects on multiple organs, with hyponatraemia (a low blood sodium...
Journal of EthnopharmacologyJanuary 30, 2025Maria Rita Garcia, Federico Ferreres, Tiago Mineiro et al.3 citations
The use of "Mexican calea" (Calea zacatechichi Schltdl.) in ritualistic ceremonies, due to its dream-inducing effects, was until recently limited to indigenous communities in Mexico. However, the plant has recently gained popularity in Western societies being commonly used in recreational settings. Despite the traditional and recreational uses, mechanisms underlying its reported oneirogenic...
Salvia divinorum Epling and Játiva is a perennial mint from the Lamiaceae family, endemic to Mexico, predominantly from the state of Oaxaca. Due to its psychoactive properties, S. divinorum had been used for centuries by Mazatecans for divinatory, religious, and medicinal purposes. In recent years, its use for recreational purposes, especially among adolescents and young adults, has...