Background: Holding a relevant ritualistic and ethnomedicinal value among the Mesoamerican tribes, Tagetes lucida Cav. has recently seen its uses being translated into Western communities, primarily for recreational ends, given its psychoactivity. Despite the new popularity resurgence of entheogens, the available data concerning this plant’s pharmacological and safety profile remain scarce...
The use of "Mexican calea" (Calea zacatechichi Schltdl.) in ritualistic ceremonies, due to its dream-inducing effects, was until recently limited to indigenous communities in Mexico. However, the plant has recently gained popularity in Western societies being commonly used in recreational settings. Despite the traditional and recreational uses, mechanisms underlying its reported oneirogenic...