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Paul Expert

6 papers in the library · 1,012 citations · publishing 2014-2023

Papers

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Altered dynamical integration/segregation balance during anesthesia-induced loss of consciousness.

Frontiers in network physiology 2023 Louis-David Lord, Timoteo Carletti, Henrique M. Fernandes et al.

In recent years, brain imaging studies have begun to shed light on the neural correlates of physiologically-reversible altered states of consciousness such as deep sleep, anesthesia, and psychedelic experiences. The emerging consensus is that normal waking consciousness requires the exploration of a dynamical repertoire enabling both global integration i.e., long-distance interactions between...

Dynamical exploration of the repertoire of brain networks at rest is modulated by psilocybin.

Neuroimage May 25, 2019 Louis-David Lord, Paul Expert, Selen Atasoy et al. 249 citations

Growing evidence from the dynamical analysis of functional neuroimaging data suggests that brain function can be understood as the exploration of a repertoire of metastable connectivity patterns ('functional brain networks'), which potentially underlie different mental processes. The present study characterizes how the brain's dynamical exploration of resting-state networks is rapidly modulated...

Conflicting emergences. Weak vs. strong emergence for the modelling of brain function.

Neuroscience and Biobehavioral Reviews April 1, 2019 Federico Turkheimer, Peter J. Hellyer, Angie A. Kehagia et al.

The concept of "emergence" has become commonplace in the modelling of complex systems, both natural and man-made; a functional property" emerges" from a system when it cannot be readily explained by the properties of the system's sub-units. A bewildering array of adaptive and sophisticated behaviours can be observed from large ensembles of elementary agents such as ant colonies, bird flocks or...

Altered trajectories in the dynamical repertoire of functional network states under psilocybin

bioRxiv (Cold Spring Harbor Laboratory) July 25, 2018 Louis-David Lord, Paul Expert, Selen Atasoy et al. 10 citations preprint

Abstract Brain activity can be understood as the exploration of a dynamical landscape of activity configurations over both space and time. This dynamical landscape may be defined in terms of spontaneous transitions within a repertoire of discrete metastable states of functional connectivity (FC), which underlie different mental processes. However, it remains unclear how the brain’s dynamical...

The brain's code and its canonical computational motifs. From sensory cortex to the default mode network: A multi-scale model of brain function in health and disease

Neuroscience & Biobehavioral Reviews May 5, 2015 Federico Turkheimer, Robert Leech, Paul Expert et al. 64 citations

A variety of anatomical and physiological evidence suggests that the brain performs computations using motifs that are repeated across species, brain areas, and modalities. The computational architecture of cortex, for example, is very similar from one area to another and the types, arrangements, and connections of cortical neurons are highly stereotyped. This supports the idea that each...

Homological scaffolds of brain functional networks

Journal of The Royal Society Interface October 29, 2014 Giovanni Petri, Paul Expert, Federico Turkheimer et al. 689 citations

Networks, as efficient representations of complex systems, have appealed to scientists for a long time and now permeate many areas of science, including neuroimaging (Bullmore and Sporns 2009 Nat. Rev. Neurosci. 10 , 186–198. ( doi:10.1038/nrn2618 )). Traditionally, the structure of complex networks has been studied through their statistical properties and metrics concerned with node and link...