Substance use & addiction journal
2026
Olivia Marcus, Brian Rush
There is an increasing interest in the use of psychedelics for the treatment of substance use disorders (SUDs) and to improve overall health and wellbeing. We aimed to update and complement research syntheses that have focused only on results from clinical trials by synthesizing the research across diverse methods to discuss implications from a broad and multi-faceted literature. We conducted a...
Nature Medicine
June 3, 2025
Chloé Pronovost-Morgan, Kyle T. Greenway, Leor Roseman et al.
26 citations
Psychedelic substances exhibit complex interactions with the 'set and setting' of use, that is, the mental state of the user and the environment in which a psychedelic experience takes place. Despite these contextual variables' known importance, psychedelic research has lacked methodological rigor in reporting extra-pharmacological factors. This study aimed to generate consensus-based...
Journal of Psychedelic Studies
January 24, 2025
Cecile Giovannetti, Anja Loizaga-Velder, Ricardo Campoy Gomez et al.
5 citations
Abstract Background The Yaqui Intercultural Medicine Clinic was established in 2020 to provide accessible, culturally-attuned treatment for substance use and mental health disorders among an Indigenous Yaqui community in Mexico. The treatment program integrates ayahuasca ceremonies and psychotherapeutic support within a community-based outpatient treatment service. This observational pilot...
Journal of Studies on Alcohol and Drugs
September 1, 2024
Brian Rush, Olivia Marcus, Sara García et al.
12 citations
This article focuses on the outcomes at 1 year post-treatment of a naturalistic evaluation of services provided through the Takiwasi Centre, an accredited Peruvian therapeutic community offering an ayahuasca-assisted, integrative treatment program for addiction rehabilitation. Participants (n = 52) completed structured interviews and a battery of validated instruments. Outcome measures included...
American Journal of Bioethics
May 2, 2024
Edward Jacobs, Brian D. Earp, Paul S. Appelbaum et al.
29 citations
The first Hopkins-Oxford Psychedelic Ethics (HOPE) workshop convened to discuss ethical matters relating to psychedelics in August 2023 at the University of Oxford.The organizers (BDE, DBY, EJ) aim...
Interdisciplinary science reviews : ISR
2023
Olivia Marcus
29 citations
Ayahuasca has a variety of traditional uses, yet there is a growing global interest in its potential therapeutic benefits for mental health conditions. Novel approaches to psychotherapy are emerging to address the needs of ayahuasca users to prepare as well as to guide them in 'integrating' their powerful psychedelic experiences, yet there is little discussion on the ethical frameworks that may...
Journal of Psychoactive Drugs
2023
Anja Loizaga-Velder, Cecile Giovannetti, Ricardo Campoy Gomez et al.
9 citations
This paper describes three case studies from an outpatient intercultural therapeutic program founded and run by Yaqui health professionals and traditional healers to serve members of the Yaqui tribe residing in Sonora, Mexico. This pilot therapeutic program has been designed specifically for Indigenous individuals, incorporating the ceremonial use of naturally derived psychedelics in addressing...
Frontiers in Pharmacology
May 19, 2021
Brian Rush, Olivia Marcus, Sara Mallén García et al.
26 citations
The present study describes the protocol for the Ayahuasca Treatment Outcome Project (ATOP) with a special focus on the evaluation of addiction treatment services provided through Takiwasi Center, the first ATOP study site. The goal of the project is to assess treatment outcomes and understand the therapeutic mechanisms of an Ayahuasca-assisted, integrative treatment model for addiction...
Mendelova univerzita v Brně eBooks
2021
Tereza Rumlerová, Olivia Marcus, Jesús M. González Mariscal et al.
2 citations
Sanz-Biset & Cañigueral, 2011), son aún escasas las publicaciones al respecto.El dispositivo de la dieta está compuesto por una serie de estrictas normas, que implican el aislamiento, pautas rigurosas de alimentación y cuidados de la actividad sexual.No se puede tomar alcohol ni tener relaciones sexuales (incluida la masturbación), además de numerosas restricciones alimenticias entre las que se...