Chronic pain is a significant health problem affecting up to 20% of Americans (Yong et al. 2022), negatively affecting overall health and quality of life, causing disability, and burdening healthca...
In the current treatment landscape, psychedelics (here broadly defined to include MDMA, 3,4-methylenedioxymethamphetamine) are under scientific investigation largely for use in chronic and treatmen...
The case raises questions regarding what constitutes employment-based risks in psychedelic research, with specific focus on workplace drug testing policies, and whether these risks merit additional...
Peterson et al. (2026) provide insightful applications of the extended mind thesis (EMT) to the care of a person with dementia (PWD) (Clark and Chalmers 1998; Gallagher 2000; Clark 2008). The EMT i...
We are grateful to those who commented on our Target Article on ethical exceptionalism around psychedelics (see Box 1 for a summary of our main points) and to Cohen and Marks (2025) for their compl...
Informed consent aims, amongst other goals, to provide robust information to prospective participants on the risks and benefits that they may incur during a study. However, participant misconceptio...
I am requesting a correction to the article “Focused Bodywork as Facilitated Communication: Cautionary Perspectives on Touch in Psychedelic Therapy” by Neşe Devenot (2025). The article contains fac...
In his work on informed consent, Daniel Villiger (2025a) credibly argues that ignorance concerning the outcomes of transformative treatments need not undermine patient autonomy, while prohibitions ...
The integration of psychedelic substances into modern Western therapeutic practice has sparked a critical examination of many topics including: efficacy of psychedelics to treat mental health diagnoses without psychotherapeutic intervention, what models of therapy to use, and ethical implications related to altered states of consciousness. Of utmost concern are issues of power dynamics leading...
Neitzke-Spruill et al. (2025) offer an important overview of the ethical considerations around the use of touch within psychedelic assisted therapies (PAT) and MDMA-assisted therapy (MDMA-AT). Thei...
In their article “Psychedelic Medicine Exceptionalism,” Cohen and Marks (2025) aim to chart a middle course between two extreme positions—the Scylla and Charybdis of psychedelic “exceptionalism” an...
As research therapists with hundreds of hours of clinical experience supporting adults with PTSD in Phase 3 trials of MDMA assisted-therapy (MAT), we appreciate the opportunity to respond to this s...
Current research on psychedelic-assisted therapy (PAT) focuses on their potential to treat clinical psychiatric conditions such as treatment-resistant depression, anxiety, and PTSD. Presumably, if ...
Cheung et al. (2025) rightly argue that psychedelics should be subject to ethical and evidentiary standards consistent with clinical medicine at large, rather than exceptionalism based on their uni...
The recent surge in psychedelic-assisted therapy (PAT) research and anticipated Food and Drug Administration (FDA) approval of MDMA (methylenedioxymethamphetamine) and psilocybin treatments has bro...
The role of touch in psychotherapy has been a topic of debate for several decades, now gaining renewed salience with the (re-)emergence of psychedelic-assisted therapy (P-AT), where altered states ...
Cohen and Marks (2025) discuss medical exceptionalism within the context of psychedelic access pathways, noting that the medical model is just one of many possible approaches to using, understandin...
When used clinically, psychedelics may appear unusual or even unique when compared to more familiar or long-standing medical interventions, prompting some to suggest that the ethical issues raised may likewise be exceptional. If that is correct, then perhaps psychedelics should be treated differently from other medical substances: for example, by being subjected to different ethical or...
Research on psychedelic medicines is experiencing a revival. Some clinicians, scientists, and ethicists believe that psychedelics are so different from other treatments that they warrant special consideration in how they are researched, regulated, commercialized, and administered. Others argue that psychedelic medicines show clinical potential, but they should be treated like other medical...
In August 2024, The U.S. Food and Drug Administration rejected Lykos Therapeutics, Inc.'s new drug application for midomafetamine with psychological intervention (MDMA-AT) to treat post-traumatic stress disorder (PTSD). Among the many issues raised during review was concern about a highly publicized case of alleged sexual misconduct by an unlicensed therapist during a Phase 2 study of MDMA and...
The presence of unusual features in psychedelic treatments has led to the argument that these treatments are exceptional within medicine and should therefore also be treated as exceptional when ana...
On August 9, 2024, the U.S. Food and Drug Administration (FDA) declined to approve Lykos Therapeutics’ application for MDMA-assisted therapy (MDMA-AT), in alignment with the recommendation of its i...
In their contribution to the rapidly developing field of research on psychedelic medicine, Glenn Cohen and Mason Marks shed light on a frequently overlooked but critical aspect of ethical considera...
of Votes 2020). Along with acknowledging that providing treatment for addiction is more beneficial than criminal charges, Measure 110 directed the state, through OHA, to create a statewide network of addiction recovery centers, providing ample grant funding to existing providers to do so
In “Distinctive but not Exceptional: The Risks of Psychedelic Ethical Exceptionalism,” Cheung et al. (2025) elaborate the ways that psychedelics share individual ethical considerations with those o...