Brain and Behavior
April 1, 2026
Livio Tarchi, Lorenzo Lasagni, Leonardo Ubaldi et al.
Schizophrenia is a severe psychiatric disorder marked by specific cognitive and clinical disturbances, for which neuroimaging biomarkers remain elusive. Novel theoretical and computational frameworks, such as integrated information decomposition, offer promising approaches to provide interpretable biomarkers for neuroimaging alterations in schizophrenia, potentially capturing disruptions...
European Journal of Neuroscience
November 1, 2025
Paolo La‐torraca‐vittori, Livio Tarchi, Elisa Arrigo et al.
1 citation
Despite a renewed scientific interest in lysergic acid diethylamide (LSD), its local neural effects remain underexplored. This functional magnetic resonance imaging (fMRI) study explored and compared LSD-induced changes in local activity (amplitude of low-frequency fluctuations: ALFF) and local connectivity (regional homogeneity: ReHo), assessing their relationship to regional receptor density....
Early Intervention in Psychiatry
November 1, 2024
Massimo Ballerini, Eleonora Rossi, Emanuele Cassioli et al.
4 citations
Psychotic-like anomalous self-experiences (ASEs) are core and early features of schizophrenia spectrum disorders, which have been recently also postulated to underlie embodiment disturbance in feeding and eating disorders (FEDs). The present study was aimed at investigating the interplay between ASEs and specific psychopathology in FED. Ninety persons with Anorexia Nervosa and 41 with Bulimia...
The Journal of Creative Behavior
June 17, 2024
Andrea Patti, Giuseppe Pierpaolo Merola, Davide Benedetti et al.
2 citations
ABSTRACT Prior studies suggest a multifaceted relationship between creativity and psychopathology, indicating that mild psychopathology might enhance creative behavior. Moreover, similar brain regions may be implicated in both creativity and psychosis. Although aberrant salience (AS) is often associated with psychotic disorders, it could also enhance creative capabilities. This study assesses...
Early Intervention in Psychiatry
December 8, 2023
Giuseppe Pierpaolo Merola, Andrea Patti, Davide Benedetti et al.
2 citations
AIM: Aberrant salience (AS) and psychotic-like experiences (PLEs) have been proven to be linked. Moreover, anxiety is a key symptom in psychosis-prone subjects and most psychotic patients. We propose a model that attempts to interpret the role of PLEs in the association between AS and anxiety among healthy controls and psychotic patients. METHODS: Demographic and psychometric data (Aberrant...
Research Square
November 20, 2023
Ottone Baccaredda Boy, Giuseppe Pierpaolo Merola, Andrea Patti et al.
Abstract the present paper describes the preliminary results of a study centered on the effect of salience alterations and cannabis use on the intensity of psychotic symptoms in adolescent and adult cohorts. The exploratory analysis focused on cross-sectional scores at psychometric questionnaires of 64 participants allocated to 4 different subgroups. A hierarchical pattern in the...
Psychopathology
2022
Andrea Patti, Gabriele Santarelli, Giulio D'Anna et al.
3 citations
Aberrant salience (AS) is an anomalous world experience which plays a major role in psychotic proneness. In the general population, a deployment of this construct - encompassing personality traits, psychotic-like symptoms, and cannabis use - could prove useful to outline the relative importance of these factors. For this purpose, 106 postgraduate university students filled the AS Inventory...