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Giovanni Castellini

2 papers in the library · 4 citations · publishing 2024-2026

Papers

Psychotic-like anomalous self-experiences in feeding and eating disorders: Their role in eating psychopathology through the mediation of body uneasiness and embodiment and identity disorders.

Early Intervention in Psychiatry November 1, 2024 Massimo Ballerini, Eleonora Rossi, Emanuele Cassioli et al. 4 citations

People with anorexia nervosa or bulimia nervosa report anomalous self-experiences (ASEs) at levels comparable to those seen in schizophrenia. In a study of 90 individuals with anorexia, 41 with bulimia, and 92 general-population controls, ASEs were strongly correlated with feeling extraneous from one's own body, body uneasiness, and eating-disorder symptoms. Statistical modeling showed that ASEs influence eating-disorder symptoms indirectly, through disturbances in embodiment, identity, and body image. The findings suggest that anomalous interoceptive processes may initiate a maladaptive cascade that impairs embodiment and selfhood in feeding and eating disorders, and that assessing ASEs could help identify an early shared vulnerability across severe disorders involving altered embodiment.

Disrupted Emergent Properties of the Brain in Schizophrenia: Insight From Integrated Information Decomposition of Resting State fMRI.

Brain and Behavior April 1, 2026 Livio Tarchi, Lorenzo Lasagni, Leonardo Ubaldi et al.

Integrated information decomposition of resting-state fMRI data from 72 people with schizophrenia and 74 healthy controls revealed that redundancy in brain connectivity was positively correlated with IQ across both groups. Within patients, information metrics were positively correlated with stereotyped thinking, preoccupation, and positive symptoms. Diagnostic accuracy reached 84.93% balanced accuracy (area under the curve = 92.30%) using redundancy. These preliminary findings suggest that information metrics may offer clinically relevant, interpretable biomarkers for schizophrenia.