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Jonathan Hamilton

2 papers in the library · 2 citations · publishing 2024-2025

Papers

Investigating change in the ability to decentre and depressive symptomatology over the course of a six-month mindfulness-based intervention in patients with persistent depression.

Psychiatry Research November 1, 2024 Jonathan Hamilton, Thorsten Barnhofer 2 citations

Decentering skills, the core ability cultivated in mindfulness-based interventions, continue to increase over six months of practice and drive reductions in depressive symptoms. In a blended online and in-person program, 44 adults with persistent depression provided self-reports at three time points. Thirty-one participants completed the intervention, averaging 68.6% of assigned practices. Statistical modeling showed that changes in decentering preceded and predicted later symptom improvements, suggesting that longer practice periods help move patients closer to recovery or remission.

Acceptability, Practicality and Preliminary Indications of Efficacy of a Blended Individual Mindfulness Intervention for Patients with Persistent Depression

Mindfulness July 1, 2025 Jonathan Hamilton, Kate Brennan, Daniel Brown et al.

A blended individual mindfulness-based intervention, combining brief therapist support with patient-led practice, shows promise for reducing depression symptoms. Of 39 patients with persistent depression who started the 12-week program, 24 completed it. Completers engaged in 89% of formal practices and showed large reductions in symptoms, with 75% moving below the clinical threshold. Patients found the approach acceptable but requested longer therapist sessions. The intervention may help make mindfulness-based treatments more accessible and sustainable for people with depression.