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Efficacy and moderators of mindfulness-based cognitive therapy (MBCT) in 'Difficult to Treat' depression: protocol for a systematic review and individual participant data meta-analysis of randomised controlled trials.

BMJ Open December 8, 2025 DOI: 10.1136/bmjopen-2025-106350 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review and individual participant data meta-analysis of randomised controlled trials Randomized Peer reviewed
Population People with difficult to treat depression
Intervention Mindfulness-based cognitive therapy
Topics Depression Meditation
Key findings The protocol outlines a planned meta-analysis to evaluate MBCT's efficacy and moderators in difficult-to-treat depression.

Abstract

Efficacy and moderators of mindfulness-based cognitive therapy (MBCT) in 'Difficult to Treat' depression: protocol for a systematic review and individual participant data meta-analysis of randomised controlled trials.