Efficacy and Moderators of Mindfulness-Based Cognitive Therapy (MBCT) in ‘Difficult to Treat’ Depression: Protocol for a Systematic Review and Individual Patient Data Meta-Analysis of Randomised Controlled Trials
medRxiv June 9, 2025 preprint DOI: 10.1101/2025.06.09.25329249 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review and individual patient data meta-analysis protocol Randomized |
|---|---|
| Population | People with 'difficult to treat' depression |
| Intervention | Mindfulness-Based Cognitive Therapy (MBCT) |
| Topics | Depression Meditation |
| Key findings | This is a protocol paper; it does not report results. The authors propose to conduct a systematic review and IPD meta-analysis to assess the efficacy of MBCT for difficult-to-treat depression and to identify moderators of treatment effect. |
Abstract
Efficacy and Moderators of Mindfulness-Based Cognitive Therapy (MBCT) in ‘Difficult to Treat’ Depression: Protocol for a Systematic Review and Individual Patient Data Meta-Analysis of Randomised Controlled Trials