Efficacy and Moderators of Mindfulness-Based Cognitive Therapy (MBCT) in ‘Difficult to Treat’ Depression: Protocol for a Systematic Review and Individual Patient Data Meta-Analysis of Randomised Controlled Trials
medRxiv June 9, 2025 preprint DOI: 10.1101/2025.06.09.25329249 (opens in new tab)
Summary
AI-generated from the abstractThis protocol describes a planned systematic review and individual patient data meta-analysis of randomised controlled trials to assess the efficacy and moderators of Mindfulness-Based Cognitive Therapy (MBCT) for people with 'difficult to treat' depression. The review will synthesize existing trial data to determine how well MBCT works and for whom it is most effective.
Study at a glance
| Characteristics | Systematic review and individual patient data meta-analysis protocol Randomized |
|---|---|
| Population | People with 'difficult to treat' depression |
| Intervention | Mindfulness-Based Cognitive Therapy (MBCT) |
Abstract
Efficacy and Moderators of Mindfulness-Based Cognitive Therapy (MBCT) in ‘Difficult to Treat’ Depression: Protocol for a Systematic Review and Individual Patient Data Meta-Analysis of Randomised Controlled Trials