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Hélène Hirbec

1 paper in the library · 83 citations · publishing 2009

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Dopamine D2High receptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil.

Synapse (New York, N.Y.) August 1, 2009 Philip Seeman, Hong-Chang Guan, Hélène Hirbec 83 citations

Although it is commonly stated that phencyclidine is an antagonist at ionotropic glutamate receptors, there has been little measure of its potency on other receptors in brain tissue. Although we previously reported that phencyclidine stimulated cloned-dopamine D2Long and D2Short receptors, others reported that phencyclidine did not stimulate D2 receptors in homogenates of rat brain striatum....