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Mercedes Lasaga

1 paper in the library · publishing 2005

Papers

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Dopamine agonist action of phencyclidine.

Synapse (New York, N.Y.) December 15, 2005 Philip Seeman, Mercedes Lasaga

Although the psychotomimetic action of phencyclidine is often used to model a hypoglutamate theory of psychosis or schizophrenia, work also exists showing that phencyclidine has a significant affinity for the dopamine D2 receptor. The present study was done to determine whether phencyclidine has a direct functional dopamine-like action on cells. The effect of phencyclidine was tested on the...