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Lei Shi

4 papers in the library · 42 citations · publishing 2020-2025

Papers

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Nightmare frequency mediates the association between childhood trauma and suicidal ideation among youth: is it sex-specific?

European Archives of Psychiatry and Clinical Neuroscience November 17, 2025 Jianyu Que, Yan’e Lu, Jingrou Liu et al.

Childhood trauma has been found to be associated with suicidal ideation among youth. However, the underlying processes that link childhood trauma and suicidal ideation are unclear. This study investigates the role of nightmare frequency in the association between childhood trauma and suicidal ideation, and the potential moderating effect of sex. Youths were recruited from Fujian Province,...

Internet-Based Self-Help Mindful Self-Compassion Intervention for Parents of Children With Cancer: A Pilot Study.

Western Journal of Nursing Research December 1, 2023 Xiangyi Tan, Yuwei Zhang, Yiling Yang et al. 4 citations

Parents of children with cancer may experience persistent psychological distress and impaired physical health throughout their children's diagnosis and treatment. This study aimed to develop a mindful self-compassion program for parents of children with cancer and explore its effect. This pre-post-test study without a control group was conducted with 34 Chinese parents of children with cancer,...

Subtle Structural Modification of a Synthetic Cannabinoid Receptor Agonist Drastically Increases its Efficacy at the CB1 Receptor

ACS Chemical Neuroscience October 17, 2023 Hideaki Yano, Rezvan Chitsazi, Christopher Lucaj et al. 12 citations

The emergence of synthetic cannabinoid receptor agonists (SCRAs) as illicit psychoactive substances has posed considerable public health risks, including fatalities. Many SCRAs exhibit much higher efficacy and potency compared with the phytocannabinoid Δ 9 -tetrahydrocannabinol (THC) at the cannabinoid receptor 1 (CB1R), leading to dramatic differences in signaling levels that can be toxic. In...

Positive Allosteric Modulation of the 5-HT1A Receptor by Indole-Based Synthetic Cannabinoids Abused by Humans

ACS Chemical Neuroscience April 23, 2020 Hideaki Yano, Pramisha Adhikari, Sett Naing et al. 26 citations

The nonmedical (i.e., recreational) misuse of synthetic cannabinoids (SCs) is a worldwide public health problem. When compared to cannabis, the misuse of SCs is associated with a higher incidence of serious adverse effects, suggesting the possible involvement of noncannabinoid sites of action. Here, we find that, unlike the phytocannabinoid Δ9-tetrahydrocannabinol, the indole-moiety containing...