ACS Omega
April 29, 2025
Cláudia Mancilha Rocha, Larissa Magalhães de Almeida Melo, Augusto César Carvalho Santos et al.
5 citations
Lysergic acid diethylamide (LSD) and phenylethylamine derivatives (NBOHs and NBOMes) are commonly found on seized blotter papers, posing public health risks. Efficient screening methods for identifying these substances are currently limited. To address this, a novel protocol combining colorimetric and electrochemical techniques was developed as a screening method for drugs of abuse in blotter...
Analytical methods : advancing methods and applications
November 14, 2024
Anne Alves Macedo, Dilton Martins Pimentel, Larissa Magalhães de Almeida Melo et al.
6 citations
In response to the growing need for sustainable analytical methods, this study explores the repurposing of screen-printed electrodes (SPEs) that would otherwise be discarded. This involves recoating the working electrode surface with a graphite (Gr) and chitosan (CTS) dispersion, creating a reusable SPE (SPE-Gr/CTS). Demonstrating its utility, SPE-Gr/CTS was employed for the detection of...
Talanta
August 15, 2024
Larissa M.a. Melo, Lucas V de Faria, Luciano C Arantes et al.
8 citations
Lysergic acid diethylamide (LSD) and two phenethylamine classes (NBOHs and NBOMes) are the main illicit drugs found in seized blotter papers. The preliminary identification of these substances is of great interest for forensic analysis. In this context, this work constitutes the inaugural demonstration of an efficient methodology for the selective detection of LSD, NBOHs, and NBOMes, utilizing...
Neuroscience Letters
June 21, 2024
Barbara G Ferri, Cintia O De Novais, Viviana C T Rojas et al.
3 citations
Sepsis-associated encephalopathy, which manifests in severe cognitive and depressive symptoms, is directly linked to neuroinflammation. Our study investigates the efficacy of 25H-NBOMe, a phenethylamine, in alleviating these symptoms, potentially offering an innovative treatment for post-sepsis depression. Wistar rats, weighing between 250-300 g, were subjected to cecal ligation and puncture...
Behavioural Brain Research
February 1, 2024
Larissa M.a. Melo, Wellington A De Barros, Ângelo de Fátima et al.
Given the critical role of maternal care in the neurodevelopment of offspring, this study aimed to investigate the effects of the psychedelic substance 25H-NBOMe on maternal behavior in lactating rats and its subsequent impact on the social and neurodevelopmental behavior of the offspring. We administered two different dosages of 25H-NBOMe (0.3mg/kg and 1.0mg/kg; i,p,) to lactating rats and...
Analytical methods : advancing methods and applications
November 9, 2023
Anne Alves Macedo, Luciano C Arantes, Dilton Martins Pimentel et al.
13 citations
Lysergic acid diethylamide (LSD) is a prevalent psychoactive substance recognized for its hallucinogenic properties, often encountered in blotter papers for illicit consumption. Given that LSD ranks among the most widely abused illicit drugs globally, its prompt identification in seized samples is vital for forensic investigations. This study presents, for the first time, an electrochemical...
European Journal of Pharmacology
September 15, 2023
Barbara G Ferri, Cintia O De Novais, Raquel S Bonani et al.
11 citations
Ring-substituted phenethylamines are believed to induce psychedelic effects primarily by interacting with 5-hydroxytryptamine 2 (5-HT2A) receptors in the brain. We assessed the effect of the psychedelic substances 25H-NBOMe and 25H-NBOH on the depressive-like behavior of male adult rats. Naive Wistar rats were divided into groups to assess the effects of different doses (0.1 mg/kg, 1 mg/kg, and...
New Journal of Chemistry
2021
Wellington Alves de Barros, Marina de Magalhães Silva, Maria Dayanne de Araújo Dantas et al.
25I-NBOH and 25I-NBOMe simultaneously bind to sites I and II of HSA, which may affect their distribution and effects.