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Recreational drugs 25I-NBOH and 25I-NBOMe bind to both Sudlow's sites I and II of human serum albumin (HSA): biophysical and molecular modeling studies

Wellington Alves de Barros, Marina de Magalhães Silva, Maria Dayanne de Araújo Dantas, Josué Carinhanha Caldas Santos, Isis Martins Figueiredo, Otávio Augusto Chaves, Carlos Mauricio R. Sant’Anna, Ângelo de Fátima

New Journal of Chemistry 2021 DOI: 10.1039/d1nj00806d (opens in new tab)

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AI-extracted from the abstract

Characteristics	Peer reviewed
Key points	25I-NBOH and 25I-NBOMe simultaneously bind to sites I and II of HSA, potentially affecting their distribution and effects.

Abstract

25I-NBOH and 25I-NBOMe simultaneously bind to sites I and II of HSA, which may affect their distribution and effects.