Recreational drugs 25I-NBOH and 25I-NBOMe bind to both Sudlow's sites I and II of human serum albumin (HSA): biophysical and molecular modeling studies
Wellington Alves de Barros, Marina de Magalhães Silva, Maria Dayanne de Araújo Dantas, Josué Carinhanha Caldas Santos, Isis Martins Figueiredo, Otávio Augusto Chaves, Carlos Mauricio R. Sant’Anna, Ângelo de Fátima
New Journal of Chemistry 2021 DOI: 10.1039/d1nj00806d (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Peer reviewed |
|---|---|
| Key points | 25I-NBOH and 25I-NBOMe simultaneously bind to sites I and II of HSA, potentially affecting their distribution and effects. |
Abstract
25I-NBOH and 25I-NBOMe simultaneously bind to sites I and II of HSA, which may affect their distribution and effects.
Citations in the library
Cites 6
- Synthesis of 25X-BOMes and 25X-NBOHs (X = H, I, Br) for pharmacological studies and as reference standards for forensic purposes January 11, 2021
- Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: high potency agonists at 5-HT2A receptors Biochemical Pharmacology September 25, 2018
- Death after 25C-NBOMe and 25H-NBOMe consumption. Forensic Science International October 1, 2017
- Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH. Drug Testing and Analysis May 1, 2017
- A fatal poisoning involving 25C-NBOMe. Forensic Science International June 1, 2015
and 1 more in the library