Psychedelic 25H-NBOMe attenuates post-sepsis depression in rats.
Neuroscience Letters June 21, 2024 Barbara G Ferri, Cintia O De Novais, Viviana C T Rojas et al. 3 citations
Sepsis-associated encephalopathy, which manifests in severe cognitive and depressive symptoms, is directly linked to neuroinflammation. Our study investigates the efficacy of 25H-NBOMe, a phenethylamine, in alleviating these symptoms, potentially offering an innovative treatment for post-sepsis depression. Wistar rats, weighing between 250-300 g, were subjected to cecal ligation and puncture...
DOI: 10.1016/j.neulet.2024.137845 (opens in new tab)
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Animal models
Forced swimming test
Long-term sequelae
Neuroinflammation
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