Frontiers in Neurology
September 1, 2026
Huan Yin, Xiaohong Guo, Yujun Gao et al.
Objective Dysfunction of the default mode network (DMN) is strongly linked to pain processing, as well as onset and progression of chronic pain disorders; however, its specific role in the pathogenesis of tension-type headache (TTH) remains incompletely understood. This study aims to explore the network homogeneity (NH) of the DMN in the pathophysiological mechanisms underlying TTH. Methods...
Communications Biology
February 26, 2026
Tianjie Li, Erin. E. Reynolds, Ziqi Wang et al.
PcncAAAD is a noncanonical fungal aromatic L-amino acid decarboxylase (AAAD) featuring a unique appendage C-terminal domain (CTD) and two metal-binding sites. Unlike its mammalian and plant counterparts, PcncAAAD is activated by calcium, although the exact activation mechanism remains unclear. Here, we establish an in silico RMSD-based evaluation model through molecular dynamics simulations,...
Research Square
April 28, 2025
Yi Wang, Tianjie Li, Erin S. Reynolds et al.
preprint
Abstract PcncAAAD is a calcium-activatable noncanonical aromatic L-amino acid decarboxylase (AAAD) featuring a unique appendage C-terminal domain (CTD) and two metal-binding sites. In this study, we establish an in silico RMSD-based evaluation model through molecular dynamics simulations, validated by in vitro enzyme assays, to decipher the enzyme’s calcium activation mechanism. Between the two...
arXiv Preprint Archive
March 18, 2025
Yi Wang
preprint
This study introduced a Multimodal Mindfulness-Training System. Our installation, 'EmotionCarrier', correlates traditional calligraphy interactions with real-time physiological data from an Apple Watch. We aim to enhance mindfulness training effectiveness, aiding in achieving physiological calmness through calligraphy practice. Our experiments with varied participant groups focused on data...
Frontiers in Public Health
August 8, 2023
Liying Li, Xue Meng, Wenting Hu et al.
30 citations
Introduction Mindfulness reflects attention to the present moment in a non-judgmental way and has been linked to individual autonomy and motivation, but conclusions are inconsistent. The purpose of this review was to summarize previous studies to explore the relationship between mindfulness and motivation and its intervention effects. Methods Literature searches were conducted in five...