The study of contemplative practices has evolved into a mature field, yet current taxonomies tend to classify all mantra-based meditation approaches as a single category, overlooking potentially different neural states induced by different mantras or different instructions. To address this gap, we conducted a study of 50 novice subjects practicing two types of mantra-based meditation over a six...
Nasal Esketamine is a rapid-acting intervention for depression, hypothesized to exert its effects through cortical disinhibition. However, the spatio-temporal dynamics of brain network activity and their relationship to the subjective drug experience following Esketamine administration remain elusive. This observational study aims to delineate brain network-level effects of Esketamine by...
Healthy brain functioning depends on balancing stable integration between brain areas for effective coordinated functioning, with bursts of desynchronisation to allow subsystems to reconfigure and express functional specialisation. Metastability, a concept originated in statistical physics and dynamical systems theory, has been proposed as a key signature that characterises this balance....