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Mark Vangel

6 papers in the library · 462 citations · publishing 2010-2023

Papers

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Mindfulness training and exercise differentially impact fear extinction neurocircuitry

Psychological Medicine September 1, 2023 Shaked E. Leibovitz, Gunes Sevinc, Jonathan Greenberg et al. 3 citations

Abstract Background The ability to extinguish a maladaptive conditioned fear response is crucial for healthy emotional processing and resiliency to aversive experiences. Therefore, enhancing fear extinction learning has immense potential emotional and health benefits. Mindfulness training enhances both fear conditioning and recall of extinguished fear; however, its effects on fear extinction...

Hippocampal circuits underlie improvements in self‐reported anxiety following mindfulness training

Brain and Behavior September 18, 2020 Gunes Sevinc, Jonathan Greenberg, Britta K. Hölzel et al. 24 citations

Abstract Introduction Mindfulness meditation has successfully been applied to cultivate skills in self‐regulation of emotion, as it employs the unbiased present moment awareness of experience. This heightened attention to and awareness of sensory experience has been postulated to create an optimal therapeutic exposure condition and thereby improve extinction learning. We recently demonstrated...

Strengthened Hippocampal Circuits Underlie Enhanced Retrieval of Extinguished Fear Memories Following Mindfulness Training.

Biological Psychiatry May 30, 2019 Gunes Sevinc, Britta K. Hölzel, Jonathan Greenberg et al.

Background: The role of hippocampus in context-dependent recall of extinction is well recognized. However, little is known about how intervention-induced changes in hippocampal networks relate to improvements in extinction learning. In this study, we hypothesized that mindfulness training creates an optimal exposure condition by heightening attention and awareness of present moment sensory...

Change in Brainstem Gray Matter Concentration Following a Mindfulness-Based Intervention is Correlated with Improvement in Psychological Well-Being

Frontiers in Human Neuroscience 2014 Omar Singleton, Britta K. Hölzel, Mark Vangel et al. 116 citations

Individuals can improve their levels of psychological well-being (PWB) through utilization of psychological interventions, including the practice of mindfulness meditation, which is defined as the non-judgmental awareness of experiences in the present moment. We recently reported that an 8-week-mindfulness-based stress reduction (MBSR) course lead to increases in gray matter concentration in...

DOI: 10.3389/fnhum.2014.00033 (opens in new tab) Pons Brainstem Tegmentum Mindfulness-based stress reduction +9

Default mode network connectivity encodes clinical pain: An arterial spin labeling study

Pain October 29, 2012 Marco L. Loggia, Jieun Kim, Randy L. Gollub et al. 319 citations

Neuroimaging studies have suggested the presence of alterations in the anatomo-functional properties of the brain of patients with chronic pain. However, investigation of the brain circuitry supporting the perception of clinical pain presents significant challenges, particularly when using traditional neuroimaging approaches. While potential neuroimaging markers for clinical pain have included...

Mindfulness practice leads to increases in regional brain gray matter density

Psychiatry Research November 10, 2010 Britta K. Hölzel, James Carmody, Mark Vangel et al.

Therapeutic interventions that incorporate training in mindfulness meditation have become increasingly popular, but to date, little is known about neural mechanisms associated with these interventions. Mindfulness-Based Stress Reduction (MBSR), one of the most widely used mindfulness training programs, has been reported to produce positive effects on psychological well-being and to ameliorate...