Psychiatry research. Neuroimaging
March 1, 2025
Michael Datko, Jacqueline Lutz, Richa Gawande et al.
1 citation
Behavior change often requires overcoming discomfort or difficult emotions. Emotional dysregulation associated with anxiety or depression may prevent behavior change initiation among people managing chronic illness. Mindfulness training may catalyze chronic disease self-management by reducing experiential avoidance of aversive experiences that act as barriers to change initiation. Using a fMRI...
Frontiers in Psychology
2025
Diane Joss, Joseph Rosansky, Paula Gardiner et al.
1 citation
Adverse childhood experiences (ACE) are transdiagnostic developmental risk factors for various mental and physical health issues, including Opioid Use Disorder (OUD). Existing research demonstrated ACE not only affects the onset, severity, and comorbidity of disorders, but also affects treatment responses. To investigate whether and how ACE modulates treatment effects of Mindfulness Based...
Global advances in integrative medicine and health
2024
Eunmi Kim, Diane Joss, Frannie Marin et al.
1 citation
Heart-Smile Training (HST) is an interoceptive compassion-based behavioral intervention that in case reports has been beneficial for depression. Interoception refers to the awareness and regulation of physiological signals from inside the body. Depressed patients often have diminished interoceptive awareness and often experience disconnection from bodily needs and sensations. In addition to...
Psychiatry research. Neuroimaging
December 1, 2022
Michael Datko, Jacqueline Lutz, Richa Gawande et al.
Interoceptive dysfunction is often present in anxiety and depression. We investigated the effects of an 8-week intervention, Mindfulness Training for Primary Care (MTPC), on brain mechanisms of interoceptive attention among patients with anxiety and/or depression. We hypothesized that fMRI brain response to interoception in the insula, a region known for interoceptive processing, would increase...
Pain medicine (Malden, Mass.)
October 1, 2020
Michael P Berry, Jacqueline Lutz, Zev Schuman-Olivier et al.
Self-compassion meditation, which involves compassion toward the self in moments of suffering, shows promise for improving pain-related functioning, but its underlying mechanisms are unknown. This longitudinal, exploratory pilot study investigated the effects of a brief (eight contact hours, two weeks of home practice) self-compassion training on pain-related brain processing in chronic low...
Expert Review of Neurotherapeutics
January 14, 2020
Rebecca Erwin Wells, Elizabeth K. Seng, Robert R Edwards et al.
74 citations
Introduction: Migraine is the second leading cause of disability worldwide, yet many patients are unable to tolerate, benefit from, or afford pharmacological treatment options. Non-pharmacological migraine therapies exist, especially to reduce opioid use, which represents a significant unmet need. Mindfulness-based interventions (MBI) have potential as a non-pharmacological treatment for...
Pain
October 29, 2012
Marco L. Loggia, Jieun Kim, Randy L. Gollub et al.
319 citations
Neuroimaging studies have suggested the presence of alterations in the anatomo-functional properties of the brain of patients with chronic pain. However, investigation of the brain circuitry supporting the perception of clinical pain presents significant challenges, particularly when using traditional neuroimaging approaches. While potential neuroimaging markers for clinical pain have included...