Non-tracheal intubation anaesthesia for thoracoscopic surgery is associated with intraoperative hypoxaemia. Esketamine has both sedative and analgesic effects, which can increase lung compliance, reduce airway resistance and relax the respiratory smooth muscles. This study will investigate the effectiveness of low-dose esketamine in reducing the incidence of intraoperative hypoxaemia and other...
Acute kidney injury (AKI) is a serious condition characterized by decreased urine output, often accompanied by psychiatric symptoms like depression. However, there are limited pharmacological treatments available for AKI and its associated depressive symptoms. In this study, we investigated whether cisplatin-induced AKI in mice leads to depression-like behaviors and whether ketamine could...
Nowadays, the prevalence of hypertension in China is still on the rise. For patients with hypertension, the combination of drug therapy and adjuvant therapy is usually used. Mindfulness Therapy as a non-medicine psychosomatic, has achieved good results in clinical application, and has become the mainstream psychological intervention technology in the treatment of chronic diseases. Mindfulness...
BACKGROUND: species that is well known for both its potent anti-addictive and neuroprotective properties. Increasing evidence supports the contributions of cAMP response element binding protein (CREB), nuclear receptor-related-1 (Nurr1), and brain-derived neurotrophic factor (BDNF) in modulating neural and behavioral plasticity which was induced by addictive drugs. OBJECTIVE: To investigate the...
As people's pace of life accelerates, the pressure of life they face is increasing. The handling of work, study, affairs and other events in daily life will bring various difficulties and problems, and people's improper handling of these events will cause mental health problems. With the continuous in-depth research of major depressive disorder researchers, researchers have found that there is...