Background: Nightmare disorder (NDO) is a clinically under-recognized sleep disorder within the military population. We have previously reported that 31.2% of patients referred to our sleep disorders center incidentally had probable NDO, yet only 3.9% were specifically referred for NDO. Under-recognition and therefore under-treatment of NDO negatively impacts patients' health and military...
Scientific ReportsJune 5, 2026Amaury C Mengin, Julie Rolling, Walid Oulehri et al.
Intensive Care Unit (ICU) hospitalizations confront individuals with imminent death and may cause post-traumatic stress disorder (PTSD). In contrast, traumatic events may lead to positive psychological outcomes such as post-traumatic growth. As consciousness is altered, near-death experiences (NDEs) may occur and be associated with post-traumatic growth. Our cross-sectional, monocentric study...
Scientific ReportsMay 21, 2026Amy Z Wang, Carissa W Tomas, Sarah Stevens et al.
Research has identified functional connectivity abnormalities in the default mode network (DMN), a functional brain network theorized to be involved in self-referential processes, among trauma survivors. Event centrality (EC) is an important cognitive component of posttrauma stress disorder (PTSD) development that heavily involves self-referential processing and autobiographical memory....
Trauma-related autobiographical memories can manifest as involuntary, vivid, emotionally charged intrusions that perpetuate avoidance, negative emotions, and functional impairment. While these memories are central to post-traumatic stress disorder (PTSD), they also occur across diagnoses and are often reported in depressive disorders, including treatment-resistant depression (TRD). Although...
Recent clinical evidence suggests that racemic 3,4-methylenedioxymethamphetamine (MDMA) might be useful for treating a range of neuropsychiatric diseases including post-traumatic stress disorder (PTSD) and depression. However, concerns about its abuse potential stemming from its monoamine releasing properties have hampered its clinical development. Thus, safer analogues of racemic MDMA with...
Trauma-related dissociation can present with derealisation, depersonalisation, abrupt lapses in awareness, memory gaps, and fugue-like states, and it may be difficult to treat with standard approaches alone. Glutamatergic interventions have been proposed as neuroplasticity-focused strategies because N-methyl-D-aspartate (NMDA) receptor antagonism and downstream...
TrialsApril 13, 2026Fanshan Huang, Weiwei Wang, Xin Miao et al.
Traumatic amputations are common traumatic injuries that require digital replantation to restore the form, function, and sensation of the hand. The post-surgical survival of replanted digits is influenced by multiple factors, including psychological factors such as posttraumatic stress disorder (PTSD), anxiety, and depression. Mindfulness-based cognitive therapy (MBCT) is considered a potential...
Sleep paralysis is a distressing parasomnia marked by temporary immobility during sleep–wake transitions, often accompanied by intense fear and hallucinatory experiences. While traditionally explained through neurophysiological mechanisms, this contemporary review highlights the significant role of psychological factors in shaping both the onset and experience of sleep paralysis episodes....
Recent research has highlighted the potential of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for the treatment of post-traumatic stress disorder and other trauma-related psychiatric conditions. However, less is known about the effects of MDMA use on psychological well-being in populations with trauma histories outside of clinical contexts. In the present study, we assessed...
Background/Objectives: Traumatic experiences may lead to both negative and positive outcomes. Positive psychological changes following trauma are commonly referred to as posttraumatic growth (PTG). The present study aims to examine factors associated with posttraumatic growth among Syrian refugees who have been living in Turkey for an extended period. Methods: This cross-sectional study...