Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning
Experimental Brain Research June 1, 2013 Briony J. Catlow, Shijie Song, Daniel Paredes et al. 266 citations
Drugs that modulate serotonin (5-HT) synaptic concentrations impact neurogenesis and hippocampal (HPC)-dependent learning. The primary objective is to determine the extent to which psilocybin (PSOP) modulates neurogenesis and thereby affects acquisition and extinction of HPC-dependent trace fear conditioning. PSOP, the 5-HT2A agonist 25I-NBMeO and the 5-HT2A/C antagonist ketanserin were...