Brain Imaging and Behavior
March 17, 2018
Jonathan Greenberg, Victoria Romero, Seth Elkin-Frankston et al.
69 citations
Proactive interference occurs when previously relevant information interferes with retaining newer material. Overcoming proactive interference has been linked to the hippocampus and deemed critical for cognitive functioning. However, little is known about whether and how this ability can be improved or about the neural correlates of such improvement. Mindfulness training emphasizes focusing on...
Military Medicine
March 1, 2018
Paul N Kizakevich, Randall Eckhoff, Janice Brown et al.
Post-traumatic stress and other problems often occur after combat, deployment, and other military operations. Because techniques such as mindfulness meditation show efficacy in improving mental health, our team developed a mobile application (app) for individuals in the armed forces with subclinical psychological problems as secondary prevention of more significant disease. Based on the...
Anthropology of Consciousness
March 1, 2018
Yochai Ataria
Abstract: The traumatic experience and the meditative experience differ in many respects. For instance, it is possible to suggest that while a sense of helplessness is the most important feature of the traumatic experience, meditation does not involve a similar sense of helplessness. Furthermore, while trauma is shocking and horrifying, meditation is considered to be constructive and efficient...
Neuropharmacology
February 21, 2018
Sean J Belouin, Jack E Henningfield
189 citations
The purpose of this commentary is to provide an introduction to this special issue of Neuropharmacology with a historical perspective of psychedelic drug research, their use in psychiatric disorders, research-restricting regulatory controls, and their recent emergence as potential breakthrough therapies for several brain-related disorders. It begins with the discovery of lysergic acid...
Psychopharmacology
February 1, 2018
Liana Fattore, Alessandro Piva, Mary Tresa Zanda et al.
Clinical data with 3,4-methylenedioxymethamphetamine (MDMA) in post-traumatic stress disorder (PTSD) patients recently stimulated interest on the potential therapeutic use of psychedelics in disorders characterized by maladaptive memories, including substance use disorders (SUD). The rationale for the use of MDMA in PTSD and SUD is being extended to a broader beneficial "psychedelic effect,"...
Frontiers in Psychiatry
2018
Christina W. Slotema, Jan Dirk Blom, Marieke B A Niemantsverdriet et al.
Background: Auditory verbal hallucinations (AVH) are experienced more frequently by patients with borderline personality disorder (BPD) than previously assumed. However, consensus is lacking on how to treat them. Objective: To provide a systematic review of studies reporting on AVH in patients with BPD, with a focus on the efficacy of treatment of psychotic symptoms. Methods: For this review a...
Chronic Stress
2018
Francesca L Schiavone, Margaret C Mckinnon, Ruth A. Lanius
To overview the phenomenology, etiology, assessment, and treatment of psychotic-like symptoms in trauma-related disorders focusing on the proposed role of temporal lobe dysfunction. We describe the literature pertaining to (i) psychotic-like symptoms and temporal lobe dysfunction in trauma-related disorders and (ii) psychological testing profiles in trauma-related disorders. We define...
Psychology
2018
Vito Zepinic
4 citations
Traumatic memories are highly emotional, life-altering events that would appear to have the best chance of persisting into the entire life. In complex trauma syndrome, they are usually endless causing often dissociative phenomena—the alterations in one’s consciousness. Thus, traumatic memories may cause a constant feeling of intense fears, helplessness, loss of control, affliction of the...
eNeuro
2018
S D Dolzani, M V Baratta, J M Moss et al.
Stress is a potent etiological factor in the onset of major depressive disorder and posttraumatic stress disorder (PTSD). Therefore, significant efforts have been made to identify factors that produce resilience to the outcomes of a later stressor, in hopes of preventing untoward clinical outcomes. The NMDA receptor antagonist ketamine has recently emerged as a prophylactic capable of...
Frontiers in Neural Circuits
2018
Tony Ye, Mitchell J Bartlett, Matthew B Schmit et al.
Introduction: Treatment-resistant depression, post-traumatic stress disorder, chronic pain, and L-DOPA-induced dyskinesia in Parkinson's disease are characterized by hypersynchronous neural oscillations. Sub-anesthetic ketamine is effective at treating these conditions, and this may relate to ketamine's capacity to reorganize oscillatory activity throughout the brain. For example, a single...