RationaleMicrodosing psychedelics-the regular consumption of small amounts of psychedelic substances such as LSD or psilocybin-is a growing trend in popular culture. Recent studies on full-dose psychedelic psychotherapy reveal promising benefits for mental well-being, especially for depression and end-of-life anxiety. While full-dose therapies include perception-distorting properties,...
Within the context of the ERC Advanced Grant Filmcolors I investigate subjectivity, affect and aesthetics from an historical perspective, drawing on ideas developed within the field of the history of emotions. However, while most of this research is of a synchronic nature, my work contains a strong diachronic component, based on Fernand Braudel’s concept of the ‘pluralité des durées’ (La...
A review of the primary role that this journal (and by extension, Dr. David Smith) has played in bearing witness to the second wave of psychedelic research as our modern-day culture embraces the current third wave of the psychedelic revival, exploring through research its therapeutic uses.
While interest in the study of psychedelic drugs has increased over much of the last decade, in this article, we argue that 2018 marked the true turning point for the field. Substantive advances in the scientific, public, and regulatory communities in 2018 significantly elevated the status and long-term outlook of psychedelic science, particularly in the United States. Advances in the...
Treatments for posttraumatic stress disorder (PTSD) have evolved significantly in the past 35 years. From what was historically viewed as a pervasive, intractable condition have emerged multiple evidence-based intervention options. These treatments, predominantly cognitive behavioral in orientation, provide significant symptom improvement in 50-60% of recipients. The treatment of PTSD with...
PURPOSE OF REVIEW: Psychedelics are reawakening interest from psychiatry, cognitive neuroscience and the general public with impressive outcomes in small-scale clinical trials, intriguing human brain imaging work and high-impact journalism. RECENT FINDINGS: This brief opinion piece offers a perspective on how psychedelics work in the brain that may help contextualize these developments. It...
With all the recent excitement about the resurgence of clinical research on the classic serotonergic psychedelics, in what has been labeled the psychedelic renaissance, it is easy to overlook a concurrent revolution taking place in the field of ketamine research. More than 50 years have passed since the synthesis of ketamine, and it remains today the most widely available compound with...
International research is increasingly demonstrating that psychedelic‐assisted psychotherapy can enhance psychotherapeutic outcomes and be effective for some treatment‐refractory mental illnesses; however, there is an absence of any such research in Australia. A review of psychedelic science has been conducted with a focus on psychedelic‐assisted psychotherapy to highlight the degree to which...
OBJECTIVE: The incidence rate of major depression in adolescents reaches approximately 14%. This disorder is usually recurrent, without remission of symptoms even after pharmacological treatment, and persists throughout adult life. Since the effects of antidepressants take approximately 2 weeks to begin, new pharmacological therapies are under continuous exploration. Recent evidence suggests...
Background. Near-death experience is an altered state of consciousness at the time when the person is on the threshold of death. Near-death experience has a specific structure which includes such elements as extra corporal experience, moving in a dark tunnel, seeing bright light, meetings with the deceased persons, panoramic life review and many others. The condition is quite common nowadays...